Speech & Language Therapy and Audiology Department, Peamount, Newcastle, Co. Dublin, Ireland.
Dysphagia. 2009 Jun;24(2):159-66. doi: 10.1007/s00455-008-9187-7. Epub 2008 Dec 16.
The impact of medications on the physiology of swallowing has received much attention in dysphagia literature. This article reviews the potential effects of medications commonly prescribed in an adult continuing care and rehabilitation facility on swallowing. An audit of medications prescribed to 153 adults accessing age-related respiratory, neurology, and learning disability services was performed. This was followed by an investigation of relevant sources to identify the potential side effects of these medications. One side effect, namely, xerostomia, which our investigations revealed could be a side effect of 24.8% of the medications used at our institution, was further investigated. The prevalence of xerostomia was then investigated in a randomly selected sample of ten subjects whose dysphagia had been confirmed by videofluoroscopy. It was found that six of the ten dysphagic clients displayed xerostomia. Review of the medications of these ten subjects indicated that all were using from three to nine drugs that could cause xerostomia. This article highlights the need for health-care professionals to consider the potential effects of these medications on swallowing and, indeed, the general presentation of clients.
药物对吞咽生理的影响在吞咽障碍文献中受到了广泛关注。本文综述了成人长期护理和康复机构中常用的药物对吞咽的潜在影响。对 153 名接受与年龄相关的呼吸、神经和学习障碍服务的成年人的处方药物进行了审核。随后，对相关来源进行了调查，以确定这些药物的潜在副作用。我们的调查显示，口干症是我们机构使用的 24.8%药物的副作用之一，进一步对此进行了研究。然后，在通过视频透视确认吞咽困难的十个随机抽样对象中调查了口干症的患病率。结果发现，十个吞咽困难的患者中有六个存在口干症。对这十个患者的药物进行审查表明，所有人都在使用三到九种可能导致口干的药物。本文强调了医疗保健专业人员需要考虑这些药物对吞咽的潜在影响，以及患者的一般表现。
