Van As Melissa, Myezwa Hellen, Stewart Aimee, Maleka Douglas, Musenge Eustasius
Department of Physiotherapy, University of the Witwatersrand, Johannesburg, South Africa.
AIDS Care. 2009 Jan;21(1):50-8. doi: 10.1080/09540120802068829.
In 2005, 16.6% of South Africans between 15 and 49 years of age were HIV positive. The advent of anti-retroviral therapy has led to improved longevity, CD4 counts and clinical well-being of people living with HIV/AIDS (PLWHA). Physical impairments, activity limitations and participation restrictions of PLWHA have profound effects on the Health-related Quality of Life and functional abilities of those with the disease, and understanding thereof may assist in the formulation of rehabilitation protocols, health care interventions as well as vocational and legislative policies. The International Classification of Function, Disability and Health (ICF) is a standardised tool, endorsed by the World Health Assembly for international use, which aims to classify functioning and disability. It is structured to assess body functions and structure, functional activities and associated personal and environmental factors.This study aimed to develop a profile of the level of functional activity, using the ICF Checklist, of an urban cohort of 45 South African individuals who are HIV positive attending an outpatient clinic at the Helen Joseph Memorial Hospital, Gauteng, South Africa. The results showed a high prevalence of physical impairments, participation restrictions and selective activity limitations and that environmental factors influence their level of ability. Specific impairments where patients had problems were mental functions (69% (n=31), sensory and pain -- 71% (n=32), digestive and metabolic functions 45% (n=20) and neuromuscular 27% (n=12). Activity limitations included major life areas' 58% (n=26), interpersonal relationships 56% (n=25), mobility 40% (n=18) and general tasks and demands 38% (n=17). Limitations in mobility were significantly associated with problems of sensory functions (p=0.05), pain (p=0.006), neuromusculoskeletal and movement-related functions (p=0.006), muscle power (p=0.006) as well as energy and drive functions (p=0.001). The study identifies the level of function and ability of PLWHA, clinical markers, and how these affect the physical, psychological and social functioning of this population.
2005年,15至49岁的南非人中有16.6%的人艾滋病毒呈阳性。抗逆转录病毒疗法的出现提高了艾滋病毒/艾滋病患者(PLWHA)的寿命、CD4细胞计数和临床健康状况。艾滋病毒/艾滋病患者的身体损伤、活动受限和参与限制对该疾病患者的健康相关生活质量和功能能力产生深远影响,了解这些情况可能有助于制定康复方案、医疗保健干预措施以及职业和立法政策。《国际功能、残疾和健康分类》(ICF)是一种标准化工具,得到世界卫生大会认可供国际使用,旨在对功能和残疾进行分类。它的结构用于评估身体功能和结构、功能活动以及相关的个人和环境因素。本研究旨在使用ICF清单,对南非豪登省海伦·约瑟夫纪念医院门诊的45名艾滋病毒呈阳性的城市人群的功能活动水平进行描述。结果显示,身体损伤、参与限制和选择性活动受限的发生率很高,并且环境因素会影响他们的能力水平。患者存在问题的具体损伤包括心理功能(69%(n=31))、感觉和疼痛——71%(n=32)、消化和代谢功能45%(n=20)以及神经肌肉功能27%(n=12)。活动受限包括主要生活领域58%(n=26)、人际关系56%(n=25)、行动能力40%(n=18)以及一般任务和要求38%(n=17)。行动能力受限与感觉功能问题(p=0.05)、疼痛(p=0.006)、神经肌肉骨骼和运动相关功能(p=0.006)、肌肉力量(p=0.006)以及能量和动力功能(p=0.001)显著相关。该研究确定了艾滋病毒/艾滋病患者的功能和能力水平、临床指标,以及这些如何影响该人群的身体、心理和社会功能。