Rasulov M T, Shahknazarov A M, Shakhnazarov M A
Gig Sanit. 2008 Sep-Oct(5):76-8.
Morphological, histochemical, and histoenzymatic studies were employed to study the morphogenetic features of acetate-induced gastric ulcer in 40 rats during chronic enteral administration of the organic chlorine pesticide hexachlorocyclohexane. The authors first established the structural and metabolic bases of mucosal regeneration defects in the region of an ulcer upon chronic enteral exposure to the toxic agent and the dose dependence of the chronic nature of acute gastric ulcer.
采用形态学、组织化学和组织酶学研究方法,对40只大鼠在长期经肠给予有机氯农药六氯环己烷期间醋酸诱导的胃溃疡的形态发生特征进行了研究。作者首先确定了在长期经肠接触毒物情况下溃疡区域黏膜再生缺陷的结构和代谢基础,以及急性胃溃疡慢性化的剂量依赖性。