Ibler Kristina, Truberg Jensen Kjeld, Ostergaard Christian, Sönksen Ute Wolff, Bruun Brita, Schønheyder Henrik C, Kemp Michael, Dargis Rimtas, Andresen Keld, Christensen Jens Jørgen
Department of Bacteriology, Mycology and Parasitology, Statens Serum Institute, Copenhagen, Denmark.
Scand J Infect Dis. 2008;40(9):761-5. doi: 10.1080/00365540802078059.
Aerococcus sanguinicola is a Gram-positive coccus first described in 2001. Infections in humans are rare but the use of 16S rRNA gene sequencing and improved phenotypic methods has facilitated the identification of A. sanguinicola. We report here 6 cases of A. sanguinicola bacteraemia, 2 of which were associated with infective endocarditis. Most patients were elderly (median age 70 y) and had underlying neurological disorders including dementia, cerebral degeneration, and myelomeningocele. The primary focus of infection was the urinary tract in 3 cases and the gallbladder in 1; no focus was detected in 2 cases. Long-term prognosis was poor reflecting the frailty of the patients. All strains were susceptible to penicillin, ampicillin, cefuroxime, vancomycin, erythromycin, and rifampicin. The optimal treatment of infection with A. sanguinicola has yet to be determined.
血栖气球菌是一种革兰氏阳性球菌，于2001年首次被描述。人类感染这种细菌的情况较为罕见，但16S rRNA基因测序和改进的表型分析方法有助于血栖气球菌的鉴定。我们在此报告6例血栖气球菌血症病例，其中2例与感染性心内膜炎相关。大多数患者为老年人（中位年龄70岁），并患有包括痴呆、脑变性和脊髓脊膜膨出在内的潜在神经系统疾病。3例患者的主要感染部位为泌尿系统，1例为胆囊；2例未检测到感染源。由于患者身体虚弱，长期预后较差。所有菌株对青霉素、氨苄西林、头孢呋辛、万古霉素、红霉素和利福平敏感。血栖气球菌感染的最佳治疗方案尚未确定。
