Michiels J F, Hofman P, Saint Paul M C, Giorsetti V, Bernard E, Vinti H, Loubière R
Laboratoire d'Anatomie Pathologique, Hôpital Pasteur, CHU de Nice.
Ann Pathol. 1991;11(3):169-75.
Three cases of intestinal microsporidiosis are reported, in acquired immunodeficiency syndrome patients, with a chronic diarrhea. The first case is associated with an intestinal cryptococcosis and with a cytomegalovirus infection and the second case was diagnosed on ileal biopsy specimen. Since the first description of Enterocytozoon bieneusi in 1985. 49 cases of intestinal microsporidiosis are reported in the literature, all in AIDS patients and the frequency of this infection is probably underrated. Prospective studies find it in 6 to 30% of cases. This parasite must be suspected in HIV seropositive patients with clinically chronic unexplained diarrhea or with intestinal atrophy.
报告了3例获得性免疫缺陷综合征患者发生肠道微孢子虫病并伴有慢性腹泻的病例。第一例与肠道隐球菌病和巨细胞病毒感染相关,第二例通过回肠活检标本确诊。自1985年首次描述比氏肠微孢子虫以来,文献中报道了49例肠道微孢子虫病病例,均为艾滋病患者,这种感染的发生率可能被低估了。前瞻性研究在6%至30%的病例中发现了这种寄生虫。对于临床上有慢性不明原因腹泻或肠道萎缩的HIV血清阳性患者,必须怀疑有这种寄生虫感染。