Dersjant-Li Yueming, Verstegen Martin W A, Gerrits Walter J J
Animal Nutrition Group, Department of Animal Science, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands.
Nutr Res Rev. 2003 Dec;16(2):223-39. doi: 10.1079/NRR200368.
In the present review, the quantitative impact of dietary aflatoxin, deoxynivalenol (DON) and fumonisin concentrations on performance of pigs and broilers is evaluated, with special emphasis on low concentrations of these toxins. Also, responses in performance of pigs and broilers to these three toxins are related to their absorption and elimination kinetics. By applying simple linear regression, information from many literature sources is integrated and condensed into, for example, estimates of depression in rates of weight gain, relative to non-contaminated diets, with increasing toxin concentrations. It was estimated that with each mg/kg increase of aflatoxin in the diet, the growth rate would be depressed by 16 % for pigs and 5 % for broilers. For DON, with each mg/kg increase in the diet, the growth depression was estimated at about 8 % for pigs, while broilers showed no response to DON concentrations below 16 mg/kg. Fumonisin showed the lowest impact on growth performance; with each mg/kg increase, the depression in growth rate was estimated at 0.4 and 0.0 % for pigs and broilers, respectively. Dietary concentrations that cause a 5 % reduction in growth rate were estimated at 0.3 and 1.0 mg/kg for aflatoxin for pigs and broilers, respectively; 1.8 and 0.6 mg/kg for pure and naturally contaminated DON for pigs, respectively; 21 and 251 mg/kg for fumonisin for pigs and broilers, respectively.
在本综述中，评估了日粮中黄曲霉毒素、脱氧雪腐镰刀菌烯醇（DON）和伏马菌素浓度对猪和肉鸡生产性能的定量影响，特别强调了这些毒素的低浓度情况。此外，猪和肉鸡对这三种毒素的生产性能反应与其吸收和消除动力学相关。通过应用简单线性回归，整合并浓缩了来自许多文献来源的信息，例如，得出随着毒素浓度增加，相对于未受污染日粮，体重增加速率降低的估计值。据估计，日粮中黄曲霉毒素每增加1毫克/千克，猪的生长速率会降低16%，肉鸡会降低5%。对于DON，日粮中每增加1毫克/千克，猪的生长抑制估计约为8%，而肉鸡在DON浓度低于16毫克/千克时无反应。伏马菌素对生长性能的影响最小；每增加1毫克/千克，猪和肉鸡的生长速率降低估计分别为0.4%和0.0%。估计导致生长速率降低5%的日粮浓度，黄曲霉毒素对猪和肉鸡分别为0.3毫克/千克和1.0毫克/千克；纯DON和天然污染DON对猪分别为1.8毫克/千克和0.6毫克/千克；伏马菌素对猪和肉鸡分别为21毫克/千克和251毫克/千克。
