Oill P A, Fiala M, Schofferman J, Byfield P E, Guze L B
Am J Med. 1977 Mar;62(3):413-7. doi: 10.1016/0002-9343(77)90840-3.
A 35 year old previously healthy physician had clinical manifestations of a mononucleosis illness complicated by arthralgia, vesicular pharyngitis and hepatitis. Initially, the patient had cytomegalovirus (CMV) viremia (predominantly in polymorphonuclear leukocytes) followed by the presence of CMV in the urine, throat and semen. He also had an antibody response to the Epstein-Barr virus which appeared to be a secondary type. During the acute phase of illness, only 7 per cent of the patient's lymphocytes formed spontaneous T cell rosettes as compared to a normal value of 65 to 70 per cent. Concurrently, evidence of abnormal delayed hypersensitivity was manifested by the loss of reactivity to mumps skin test antigen. All clinical and laboratory abnormalities except for the persistence of CMV in the pharynx, urine and semen returned to normal after resolution of the clinical illness.
一名35岁既往健康的内科医生出现了传染性单核细胞增多症的临床表现，并伴有关节痛、水疱性咽炎和肝炎。起初，患者出现巨细胞病毒（CMV）病毒血症（主要存在于多形核白细胞中），随后尿液、咽喉和精液中也出现了CMV。他对EB病毒也有抗体反应，这似乎是继发类型。在疾病急性期，患者仅有7%的淋巴细胞形成自发性T细胞玫瑰花结，而正常值为65%至70%。同时，对腮腺炎皮肤试验抗原反应性丧失表明存在异常的迟发型超敏反应。除了CMV在咽部、尿液和精液中持续存在外，所有临床和实验室异常在临床疾病缓解后均恢复正常。
