环磷酸鸟苷（cGMP）、鸟苷酸环化酶及cGMP依赖性蛋白激酶简史
A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases.
作者信息
Kots Alexander Y, Martin Emil, Sharina Iraida G, Murad Ferid
机构信息
The University of Texas Health Science Center at Houston, Institute of Molecular Medicine, 1825 Pressler St., Houston, TX 77030, USA.
出版信息
Handb Exp Pharmacol. 2009(191):1-14. doi: 10.1007/978-3-540-68964-5_1.
Abstract
Here, we review the early studies on cGMP, guanylyl cyclases, and cGMP-dependent protein kinases to facilitate understanding of development of this exciting but complex field of research encompassing pharmacology, biochemistry, physiology, and molecular biology of these important regulatory molecules.
摘要
在此，我们回顾了关于环磷酸鸟苷（cGMP）、鸟苷酸环化酶和cGMP依赖性蛋白激酶的早期研究，以促进对这一令人兴奋但复杂的研究领域发展的理解，该领域涵盖了这些重要调节分子的药理学、生物化学、生理学和分子生物学。
相似文献
1
A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases.环磷酸鸟苷（cGMP）、鸟苷酸环化酶及cGMP依赖性蛋白激酶简史
Handb Exp Pharmacol. 2009(191):1-14. doi: 10.1007/978-3-540-68964-5_1.
2
Guanylyl cyclases and signaling by cyclic GMP.鸟苷酸环化酶与环磷酸鸟苷信号传导
Pharmacol Rev. 2000 Sep;52(3):375-414.
3
Cyclic GMP and ion channel regulation.环磷酸鸟苷与离子通道调节
Adv Second Messenger Phosphoprotein Res. 1999;33:251-77. doi: 10.1016/s1040-7952(99)80013-5.
4
Membrane guanylate cyclase signal transduction system.膜鸟苷酸环化酶信号转导系统
Indian J Biochem Biophys. 1997 Feb-Apr;34(1-2):40-9.
5
Interlude of cGMP and cGMP/protein kinase G type 1 in pancreatic adenocarcinoma cells.环磷酸鸟苷（cGMP）与环磷酸鸟苷/蛋白激酶G1型在胰腺腺癌细胞中的中间阶段
Pancreas. 2014 Jul;43(5):784-94. doi: 10.1097/MPA.0000000000000104.
6
Comparative analysis between cyclic GMP and cyclic AMP signalling in human sperm.人类精子中环状鸟苷单磷酸与环状腺苷单磷酸信号传导的比较分析。
Mol Hum Reprod. 2004 Jul;10(7):543-52. doi: 10.1093/molehr/gah065. Epub 2004 Apr 30.
7
Calmodulin Regulates Ciliary Beats in the Human Nasal Mucosa Through Adenylate/Guanylate Cyclases and Protein Kinases A/G.钙调蛋白通过腺苷酸/鸟苷酸环化酶和蛋白激酶 A/G 调节人鼻黏膜纤毛摆动。
Int Arch Allergy Immunol. 2021;182(9):800-806. doi: 10.1159/000515225. Epub 2021 Apr 21.
8
Molecular variants of soluble guanylyl cyclase affecting cardiovascular risk.影响心血管风险的可溶性鸟苷酸环化酶的分子变体
Circ J. 2015;79(3):463-9. doi: 10.1253/circj.CJ-15-0025. Epub 2015 Feb 6.
9
Cyclic GMP metabolism and its role in brain physiology.环磷酸鸟苷代谢及其在脑生理学中的作用。
J Physiol Pharmacol. 2005 Mar;56 Suppl 2:15-34.
10
Different effects of soluble and particulate guanylyl cyclases on expression of inflammatory cytokines in rat peripheral blood mononuclear cells.可溶性和颗粒型鸟苷酸环化酶对大鼠外周血单个核细胞炎症细胞因子表达的不同影响。
Immunobiology. 2011 Mar;216(3):423-30. doi: 10.1016/j.imbio.2010.06.006. Epub 2010 Jul 24.
引用本文的文献
1
Regulation and Pharmacology of the Cyclic GMP and Nitric Oxide Pathway in Embryonic and Adult Stem Cells.胚胎和成体干细胞中环鸟苷酸和一氧化氮途径的调节与药理学
Cells. 2024 Dec 5;13(23):2008. doi: 10.3390/cells13232008.
2
Nitric Oxide as a Central Molecule in Hypertension: Focus on the Vasorelaxant Activity of New Nitric Oxide Donors.一氧化氮作为高血压的核心分子：聚焦新型一氧化氮供体的血管舒张活性
Biology (Basel). 2021 Oct 14;10(10):1041. doi: 10.3390/biology10101041.
3
Targeting Protein Kinase G to Treat Cardiac Proteotoxicity.靶向蛋白激酶G治疗心脏蛋白毒性
Front Physiol. 2020 Jul 28;11:858. doi: 10.3389/fphys.2020.00858. eCollection 2020.
4
Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation.四氢生物蝶呤通过 S-亚硝基化调节泛素与 UBC13/UBE2N 的连接和蛋白酶体活性。
Sci Rep. 2018 Sep 25;8(1):14310. doi: 10.1038/s41598-018-32481-4.
5
Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase-mediated S-nitrosylation.刺激大脑烟碱型乙酰胆碱受体通过脑诱导型一氧化氮合酶介导的 S-亚硝化作用激活肾上腺髓质流出。
Br J Pharmacol. 2018 Oct;175(19):3758-3772. doi: 10.1111/bph.14445. Epub 2018 Aug 12.
6
Vitamin C Deficiency Reduces Muscarinic Receptor Coronary Artery Vasoconstriction and Plasma Tetrahydrobiopterin Concentration in Guinea Pigs.维生素C缺乏会降低豚鼠毒蕈碱受体介导的冠状动脉血管收缩及血浆四氢生物蝶呤浓度。
Nutrients. 2017 Jul 3;9(7):691. doi: 10.3390/nu9070691.
7
The lost language of the RNA World.RNA世界失落的语言。
Sci Signal. 2017 Jun 13;10(483):eaam8812. doi: 10.1126/scisignal.aam8812.
8
Compartmentalized cGMP Responses of Olfactory Sensory Neurons in .嗅觉感觉神经元在……中的区域化环磷酸鸟苷反应
J Neurosci. 2017 Apr 5;37(14):3753-3763. doi: 10.1523/JNEUROSCI.2628-16.2017. Epub 2017 Mar 7.
9
Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.老狗学新招：蛋白激酶G的新型心脏靶点与应激调节
Cardiovasc Res. 2016 Jul 15;111(2):154-62. doi: 10.1093/cvr/cvw107. Epub 2016 Jun 13.
10
3D Motions of Iron in Six-Coordinate {FeNO}(7) Hemes by Nuclear Resonance Vibration Spectroscopy.通过核磁共振振动光谱法研究六配位{FeNO}(7)血红素中铁的三维运动
Chemistry. 2016 Apr 25;22(18):6323-6332. doi: 10.1002/chem.201505155. Epub 2016 Mar 21.
本文引用的文献
1
ONE-GC membrane guanylate cyclase, a trimodal odorant signal transducer.单通道鸟苷酸环化酶，一种三模态气味信号转导器。
Biochem Biophys Res Commun. 2008 Mar 7;367(2):440-5. doi: 10.1016/j.bbrc.2007.12.153. Epub 2008 Jan 4.
2
Contribution of the receptor guanylyl cyclase GC-D to chemosensory function in the olfactory epithelium.受体鸟苷酸环化酶GC-D对嗅上皮化学感觉功能的贡献。
Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14507-12. doi: 10.1073/pnas.0704965104. Epub 2007 Aug 27.
3
Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development.沙塔克讲座。细胞信号传导与药物开发中的一氧化氮和环磷酸鸟苷
N Engl J Med. 2006 Nov 9;355(19):2003-11. doi: 10.1056/NEJMsa063904.
4
Nitric oxide and the endothelium: history and impact on cardiovascular disease.一氧化氮与内皮：历史及其对心血管疾病的影响
Vascul Pharmacol. 2006 Nov;45(5):268-76. doi: 10.1016/j.vph.2006.08.002. Epub 2006 Aug 17.
5
Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation.由δ-氨基乙酰丙酸生成原卟啉IX可引起肺动脉舒张和可溶性鸟苷酸环化酶激活。
Am J Physiol Lung Cell Mol Physiol. 2006 Sep;291(3):L337-44. doi: 10.1152/ajplung.00482.2005.
6
Smooth muscle of telokin-deficient mice exhibits increased sensitivity to Ca2+ and decreased cGMP-induced relaxation.端激酶缺陷小鼠的平滑肌对Ca2+的敏感性增加，且cGMP诱导的舒张作用减弱。
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2440-5. doi: 10.1073/pnas.0508566103. Epub 2006 Feb 6.
7
Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase.激活血红素氧化型可溶性鸟苷酸环化酶的新型邻氨基苯甲酸衍生物的生物化学与药理学
Mol Pharmacol. 2006 Apr;69(4):1260-8. doi: 10.1124/mol.105.018747. Epub 2005 Dec 6.
8
Cyclic GMP transporters.环磷酸鸟苷转运体
Neurochem Int. 2004 Nov;45(6):865-73. doi: 10.1016/j.neuint.2004.03.017.
9
CCAAT-binding factor regulates expression of the beta1 subunit of soluble guanylyl cyclase gene in the BE2 human neuroblastoma cell line.CCAAT结合因子调控BE2人神经母细胞瘤细胞系中可溶性鸟苷酸环化酶基因β1亚基的表达。
Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11523-8. doi: 10.1073/pnas.1934338100. Epub 2003 Sep 22.
10
Isolation of adenosine 3', 5'-monophosphate and guanosine 3', 5'-monophosphate from rat urine.从大鼠尿液中分离3',5'-环磷酸腺苷和3',5'-环磷酸鸟苷。
Biochem Biophys Res Commun. 1963 May 22;11:330-4. doi: 10.1016/0006-291x(63)90566-7.
Zotero 插件