• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过对突尼斯线粒体DNA H单倍群的精细表征揭示末次盛冰期后从伊比利亚到北非的扩张

Post-last glacial maximum expansion from Iberia to North Africa revealed by fine characterization of mtDNA H haplogroup in Tunisia.

作者信息

Cherni Lotfi, Fernandes Verónica, Pereira Joana B, Costa Marta D, Goios Ana, Frigi Sabeh, Yacoubi-Loueslati Besma, Amor Mohamed Ben, Slama Abdelhakim, Amorim António, El Gaaied Amel Ben Ammar, Pereira Luísa

机构信息

Laboratory of Genetics Immunology and Human Pathology, Faculty of Sciences of Tunis, Tunisia.

出版信息

Am J Phys Anthropol. 2009 Jun;139(2):253-60. doi: 10.1002/ajpa.20979.

DOI:10.1002/ajpa.20979
PMID:19090581
Abstract

The first large-scale fine characterization of Tunisian H lineages clarifies that the post-Last glacial maximum expansion originating in Iberia not only led to the resettlement of Europe but also of North Africa. We found that 46% of 81 Tunisian H lineages subscreened for 1,580 bp in mtDNA coding region were affiliated with H1 and H3 subhaplogroups, which are known to have originated in Iberia. Although no signs of local expansion were detected, which would allow a clear dating of their introduction, the younger and less diverse Tunisian H1 and H3 lineages indicate Iberia as the radiating centre. Major contributions from historical migrations to this Iberian genetic imprint in Tunisia were ruled out by the mtDNA gene pool similarity between Berber/Arab/cosmopolitan samples and some "Andalusian" communities, settled by the descendents of the "Moors" who once lived in Iberia for 10 centuries (between 8th and 17th centuries), before being expelled to Tunisia.

摘要

对突尼斯H谱系的首次大规模精细表征表明,末次盛冰期后起源于伊比利亚半岛的扩张不仅导致了欧洲的重新定居,也导致了北非的重新定居。我们发现,在mtDNA编码区对1580 bp进行亚筛选的81个突尼斯H谱系中,46%与已知起源于伊比利亚半岛的H1和H3亚单倍群相关。尽管未检测到本地扩张的迹象,从而无法明确确定它们引入的时间,但较年轻且多样性较低的突尼斯H1和H3谱系表明伊比利亚半岛是辐射中心。柏柏尔人/阿拉伯人/国际化样本与一些“安达卢西亚”社区之间的mtDNA基因库相似性排除了历史移民对突尼斯这种伊比利亚基因印记的主要贡献,这些“安达卢西亚”社区是由曾经在伊比利亚半岛生活了10个世纪(8世纪至17世纪),后被驱逐到突尼斯的“摩尔人”后裔定居的。

相似文献

1
Post-last glacial maximum expansion from Iberia to North Africa revealed by fine characterization of mtDNA H haplogroup in Tunisia.通过对突尼斯线粒体DNA H单倍群的精细表征揭示末次盛冰期后从伊比利亚到北非的扩张
Am J Phys Anthropol. 2009 Jun;139(2):253-60. doi: 10.1002/ajpa.20979.
2
Mitochondrial DNA heterogeneity in Tunisian Berbers.突尼斯柏柏尔人的线粒体DNA异质性。
Ann Hum Genet. 2004 May;68(Pt 3):222-33. doi: 10.1046/j.1529-8817.2004.00096.x.
3
High-resolution mtDNA evidence for the late-glacial resettlement of Europe from an Iberian refugium.来自伊比利亚避难所的欧洲末次冰期晚期重新定居的高分辨率线粒体DNA证据。
Genome Res. 2005 Jan;15(1):19-24. doi: 10.1101/gr.3182305.
4
Phylogeographic inferences from the mtDNA variation of the three-toed skink, Chalcides chalcides (Reptilia: Scincidae).基于三趾石龙子(Chalcides chalcides,爬行纲:石龙子科)线粒体DNA变异的系统地理学推断
J Exp Zool B Mol Dev Evol. 2007 May 15;308(3):297-307. doi: 10.1002/jez.b.21149.
5
Polymorphisms of mtDNA control region in Tunisian and Moroccan populations: an enrichment of forensic mtDNA databases with Northern Africa data.突尼斯和摩洛哥人群线粒体DNA控制区的多态性:为法医学线粒体DNA数据库增添北非数据。
Forensic Sci Int Genet. 2009 Jun;3(3):166-72. doi: 10.1016/j.fsigen.2009.01.014. Epub 2009 Feb 25.
6
Early Holocenic and Historic mtDNA African Signatures in the Iberian Peninsula: The Andalusian Region as a Paradigm.伊比利亚半岛早期全新世和历史时期的非洲线粒体DNA特征:以安达卢西亚地区为例
PLoS One. 2015 Oct 28;10(10):e0139784. doi: 10.1371/journal.pone.0139784. eCollection 2015.
7
Mitochondrial DNA sequence variation in Portuguese native dog breeds: diversity and phylogenetic affinities.葡萄牙本土犬种的线粒体DNA序列变异:多样性与系统发育亲缘关系
J Hered. 2006 Jul-Aug;97(4):318-30. doi: 10.1093/jhered/esl006. Epub 2006 Jul 3.
8
Mitochondrial DNA haplogroup H structure in North Africa.北非的线粒体DNA单倍群H结构
BMC Genet. 2009 Feb 25;10:8. doi: 10.1186/1471-2156-10-8.
9
Phylogeography of Southern Water Vole (Arvicola sapidus): evidence for refugia within the Iberian glacial refugium?南方水田鼠(Arvicola sapidus)的系统地理学:伊比利亚冰川避难所内存在避难所的证据?
Mol Ecol. 2009 Sep;18(17):3652-67. doi: 10.1111/j.1365-294X.2009.04297.x. Epub 2009 Aug 10.
10
Predominant African-derived mtDNA in Caribbean and Brazilian Creole cattle is also found in Spanish cattle (Bos taurus).在加勒比和巴西克里奥尔牛中占主导地位的源自非洲的线粒体DNA(mtDNA)在西班牙牛(Bos taurus)中也有发现。
J Hered. 2004 Sep-Oct;95(5):450-3. doi: 10.1093/jhered/esh070.

引用本文的文献

1
Moroccan genome project: genomic insight into a North African population.摩洛哥基因组计划:对北非人群的基因组洞察
Commun Biol. 2025 Apr 9;8(1):584. doi: 10.1038/s42003-025-08020-z.
2
Genetic diversity of North African populations in the 17q21 genomic region.北非人群在 17q21 基因组区域的遗传多样性。
Mamm Genome. 2024 Sep;35(3):445-460. doi: 10.1007/s00335-024-10051-6. Epub 2024 Jul 4.
3
Shrouded in history: Unveiling the ways of life of an early Muslim population in Santarém, Portugal (8th- 10th century AD).历史的面纱:揭开葡萄牙圣塔伦早期穆斯林人口的生活方式(公元 8 世纪-10 世纪)。
PLoS One. 2024 Mar 6;19(3):e0299958. doi: 10.1371/journal.pone.0299958. eCollection 2024.
4
Isotopic evidence for human mobility in late antique Bulla Regia (Tunisia).古晚期布勒亚雷亚(突尼斯)人类流动性的同位素证据。
J Archaeol Sci Rep. 2023 Feb;47:103816. doi: 10.1016/j.jasrep.2022.103816.
5
African mitochondrial haplogroup L7: a 100,000-year-old maternal human lineage discovered through reassessment and new sequencing.非洲线粒体单倍群 L7:通过重新评估和新测序发现的一个 10 万年历史的母系人类谱系。
Sci Rep. 2022 Jun 24;12(1):10747. doi: 10.1038/s41598-022-13856-0.
6
Autoantibodies to Zinc Transporter 8 and Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa.自身抗体锌转运体 8 与 1 型糖尿病儿童基因型:北非的开创性研究。
J Diabetes Res. 2022 May 23;2022:2539871. doi: 10.1155/2022/2539871. eCollection 2022.
7
New Insight into the human genetic diversity in North African populations by genotyping of SNPs in DRD3, CSMD1 and NRG1 genes.通过对 DRD3、CSMD1 和 NRG1 基因中的 SNP 进行基因分型,深入了解北非人群的人类遗传多样性。
Mol Genet Genomic Med. 2022 Mar;10(3):e1871. doi: 10.1002/mgg3.1871. Epub 2022 Feb 7.
8
Mitochondrial DNA and Alzheimer's disease: a first case-control study of the Tunisian population.线粒体DNA与阿尔茨海默病:突尼斯人群的首例病例对照研究。
Mol Biol Rep. 2022 Mar;49(3):1687-1700. doi: 10.1007/s11033-021-06978-7. Epub 2021 Dec 1.
9
Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population.突尼斯中东父系基因库的研究:阿拉伯人群中 T-M70 单倍群的高流行率。
Sci Rep. 2021 Aug 3;11(1):15728. doi: 10.1038/s41598-021-95144-x.
10
Human Genomic Diversity Where the Mediterranean Joins the Atlantic.地中海与大西洋交汇处的人类基因组多样性。
Mol Biol Evol. 2020 Apr 1;37(4):1041-1055. doi: 10.1093/molbev/msz288.