Battaglia Cesare, Nappi Rossella E, Mancini Fulvia, Cianciosi Arianna, Persico Nicola, Busacchi Paolo, Facchinetti Fabio, Sisti Giovanni
Department of Obstetrics and Gynecology, University of Bologna, Bologna, Italy.
J Sex Med. 2008 Dec;5(12):2886-94. doi: 10.1111/j.1743-6109.2008.01010.x.
In polycystic ovarian syndrome (PCOS) women, the changes in body appearance (mainly obesity and hirsutism) may influence the feminine identity of the patients with consequent depression and sexual disturbances.
To evaluate if lean PCOS patients present an increased incidence of depression and sexual dysfunction in comparison with controls and if clitoral volume and vascularization are influenced by circulating androgens levels.
25 lean PCOS women (Group I) and 18 healthy nonhirsute volunteers (Group II) were submitted, on day 3-5 of the cycle, to ultrasonographic and Doppler analyses, and to hormonal and biochemical evaluations.
Utero-ovarian and clitoral ultrasonographic analysis, and color Doppler evaluation of the uterine, stromal ovarian, and dorsal clitoral arteries. Hormonal and nitrites/nitrates plasma concentrations were analyzed. Each woman filled in the 2-factor Italian McCoy female questionnaire (MFSQ) and the Beck's Depression Inventory questionnaire (BDI).
Androgens resulted, as expected, more elevated in PCOS patients than in controls. However, the ultrasonographic (US) assessment of the clitoral body volume evidenced no significant differences between PCOS (0.72+/-0.41 mL) and control (0.62+/-0.20 mL) patients. The resistances registered at the level of the dorsal clitoral artery did not show any difference between Group I (PI=1.55+/-0.40) and Group II (PI=1.79+/-0.38). The 2-factor Italian MFSQ and the BDI did not show any difference between PCOS women and controls.
In PCOS women, probably, the moderate hirsutism and hyperandrogenism do not induce the sense of loss of feminine identity and have no impact on sexual self-worth and sexual satisfaction.
在多囊卵巢综合征（PCOS）女性中，身体外观的变化（主要是肥胖和多毛）可能会影响患者的女性身份认同，进而导致抑郁和性功能障碍。
评估与对照组相比，体型偏瘦的PCOS患者是否有更高的抑郁和性功能障碍发生率，以及阴蒂体积和血管化是否受循环雄激素水平的影响。
在月经周期的第3 - 5天，对25名体型偏瘦的PCOS女性（第一组）和18名健康无多毛症状的志愿者（第二组）进行超声和多普勒分析、激素及生化评估。
子宫卵巢及阴蒂超声分析，子宫、卵巢间质及阴蒂背动脉的彩色多普勒评估。分析激素及血浆亚硝酸盐/硝酸盐浓度。每位女性填写两因素意大利麦考伊女性问卷（MFSQ）和贝克抑郁量表问卷（BDI）。
正如预期，PCOS患者的雄激素水平高于对照组。然而，阴蒂体体积的超声（US）评估显示，PCOS患者（0.72±0.41 mL）与对照组患者（0.62±0.20 mL）之间无显著差异。第一组（PI = 1.55±0.40）和第二组（PI = 1.79±0.38）在阴蒂背动脉水平测得的阻力无差异。两因素意大利MFSQ和BDI在PCOS女性和对照组之间未显示出任何差异。
在PCOS女性中，中度多毛和高雄激素血症可能不会导致女性身份认同感的丧失，对性自我价值和性满意度也没有影响。
