Harada Yukinori, Hirose Naofumi, Kubota Toshiaki, Tawara Akihiko
Department of Ophthalmology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu-shi, Fukuoka, Japan.
J Glaucoma. 2008 Dec;17(8):619-25. doi: 10.1097/IJG.0b013e3181634f0f.
The aim of this study was to examine whether or not central corneal thickness (CCT) and corneal curvature radius (CCR) influence the concordance of intraocular pressure (IOP) readings taken with a noncontact tonometer (NCT) and a Goldmann applanation tonometer (GAT).
Eighty-seven eyes from 87 patients without any histories of intraocular operation were enrolled in the present study. We calculated the difference in IOP readings between the 2 methods (NCT-GAT), and then examined the relationship between the IOP readings, and CCT and CCR using a linear regression line.
IOP measured by both NCT (r=0.515, P<0.0001) and GAT (r=0.237, P<0.05) was significantly correlated with CCT. NCT readings were significantly higher in the thicker group (CCT>or=526.9 microm) than in the thinner group (CCT<526.9 microm) (P<0.005). GAT readings had no difference between the thicker and thinner groups. IOP measured by GAT (r=-0.261, P<0.05), but not that measured by NCT (r=-0.111, P=0.3042), showed a significant negative correlation with CCR. An IOP value of (NCT-GAT) had a significant positive correlation with not only CCT (r=0.666, P<0.0001) but also CCR (r=0.227, P<0.05). The value of (NCT-GAT) was significantly higher in the thicker group than in the thinner group (P<0.005).
NCT can be more affected by CCT than GAT. CCR could influence the measurements of GAT, but not those by NCT. CCT and CCR can therefore influence the discordance of IOP readings taken with NCT and GAT.
本研究旨在探讨中央角膜厚度(CCT)和角膜曲率半径(CCR)是否会影响使用非接触眼压计(NCT)和戈德曼压平眼压计(GAT)测量的眼压读数的一致性。
本研究纳入了87例无任何眼内手术史患者的87只眼。我们计算了两种方法(NCT - GAT)测得的眼压读数差异,然后使用线性回归线研究眼压读数与CCT和CCR之间的关系。
NCT(r = 0.515,P < 0.0001)和GAT(r = 0.237,P < 0.05)测量的眼压均与CCT显著相关。较厚组(CCT≥526.9微米)的NCT读数显著高于较薄组(CCT < 526.9微米)(P < 0.005)。较厚组和较薄组的GAT读数无差异。GAT测量的眼压(r = - 0.261,P < 0.05)与CCR呈显著负相关,而NCT测量的眼压(r = - 0.111,P = 0.3042)与CCR无显著相关性。(NCT - GAT)的眼压值不仅与CCT(r = 0.666,P < 0.0001)显著正相关,还与CCR(r = 0.227,P < 0.05)显著正相关。较厚组的(NCT - GAT)值显著高于较薄组(P < 0.005)。
与GAT相比,NCT受CCT的影响更大。CCR会影响GAT的测量结果,但不影响NCT的测量结果。因此,CCT和CCR会影响使用NCT和GAT测量的眼压读数的不一致性。