Psaty Estee L, Halpern Allan C
Department of Dermatology, Memorial Sloan-Kettering Cancer Center, 160 East 53rd Street, New York, NY 10022, USA.
Clin Dermatol. 2009 Jan-Feb;27(1):35-45. doi: 10.1016/j.clindermatol.2008.09.004.
Relative to other specialties, dermatologists have been slow to adopt advanced technologic diagnostic aids. Most skin disease can be diagnosed by simple visual inspection, and the skin is readily accessible for a diagnostic biopsy. Diagnostic aids, such as total body photography and dermoscopy, improve the clinician's ability to diagnose melanoma beyond unaided visual inspection, however, and are now considered mainstream methods for early detection. Emerging technologies such as in vivo reflectance confocal microscopy are currently being investigated to determine their utility for noninvasive diagnosis of melanoma. This review summarizes the currently available cutaneous imaging devices and new frontiers in noninvasive diagnosis of skin disease. We anticipate that multimodal systems that combine different imaging technologies will further improve our ability to detect, at the bedside, melanoma at an earlier stage.
与其他专科相比，皮肤科医生采用先进技术诊断辅助手段的速度一直较慢。大多数皮肤病通过简单的目视检查即可诊断，而且皮肤易于进行诊断性活检。然而，诸如全身摄影和皮肤镜检查等诊断辅助手段提高了临床医生在仅凭肉眼检查之外诊断黑色素瘤的能力，现在已被视为早期检测的主流方法。诸如体内反射式共聚焦显微镜等新兴技术目前正在进行研究，以确定其在黑色素瘤无创诊断中的效用。本综述总结了目前可用的皮肤成像设备以及皮肤病无创诊断的新领域。我们预计，结合不同成像技术的多模态系统将进一步提高我们在床边更早检测出黑色素瘤的能力。
