Perry Stephanie M, Getz Charles L, Soslowsky Louis J
McKay Orthopaedic Research Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA.
J Shoulder Elbow Surg. 2009 Jan-Feb;18(1):52-7. doi: 10.1016/j.jse.2008.07.003.
Although presumed, damage in the remaining (intact) rotator cuff tendons in the presence of an isolated supraspinatus tendon tear or multiple tendon tear has not been well studied. This study used an animal model of multiple rotator cuff tendon tears to investigate alterations in the remaining (intact) tendon mechanical properties at 4 and 8 weeks after injury. Twenty-four rats served as uninjured controls, whereas 72 were divided among 3 tendon detachment groups: supraspinatus tendon detachment, supraspinatus + infraspinatus tendon detachment, and supraspinatus + subscapularis tendon detachment. The remaining (intact) rotator cuff tendons had decreased mechanical properties in the presence of rotator cuff tears. The remaining (intact) subscapularis and infraspinatus tendon cross-sectional areas increased, whereas tendon modulus decreased after tears of both 1 and 2 tendons. The remaining (intact) tendon cross-sectional areas continued to increase with time after injury. These alterations could potentially lead to further tendon damage and tear progression.
尽管据推测,在存在孤立的冈上肌腱撕裂或多条肌腱撕裂的情况下,其余(完整)的肩袖肌腱损伤尚未得到充分研究。本研究使用了一种多条肩袖肌腱撕裂的动物模型,以研究损伤后4周和8周时其余(完整)肌腱力学性能的变化。24只大鼠作为未受伤的对照,而72只大鼠被分为3个肌腱切断组:冈上肌腱切断、冈上肌+冈下肌腱切断以及冈上肌+肩胛下肌腱切断。在存在肩袖撕裂的情况下,其余(完整)的肩袖肌腱力学性能下降。在1条和2条肌腱撕裂后,其余(完整)的肩胛下肌和冈下肌腱横截面积增加,而肌腱模量下降。损伤后,其余(完整)肌腱的横截面积随时间持续增加。这些改变可能会导致进一步的肌腱损伤和撕裂进展。