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与组织胞浆菌病相关的重建炎症综合征，伴HIV感染中的噬血细胞综合征。

Reconstitution inflammatory syndrome related to histoplasmosis, with a hemophagocytic syndrome in HIV infection.

作者信息

De Lavaissière Marc, Manceron Véronique, Bourée Patrice, Garçon Loïc, Bisaro Francine, Delfraissy Jean-François, Lambotte Olivier, Goujard Cécile

机构信息

Service de Médecine Interne, Hôpital Bicêtre, AP-HP, Le Kremlin Bicêtre, France.

出版信息

J Infect. 2009 Mar;58(3):245-7. doi: 10.1016/j.jinf.2008.11.010. Epub 2008 Dec 17.

DOI:10.1016/j.jinf.2008.11.010
PMID:19095307
Abstract

Immune reconstitution after initiation of antiretroviral therapy may unmask a latent infection. We report a case of disseminated Histoplasma capsulatum capsulatum infection associated with a hemophagocytic syndrome in an HIV-infected patient, three weeks after initiation of antiretroviral therapy. The immune reconstitution inflammatory syndrome might be a risk factor for hemophagocytosis.

摘要

开始抗逆转录病毒治疗后免疫重建可能会使潜伏感染显现出来。我们报告了1例HIV感染患者在开始抗逆转录病毒治疗3周后发生播散性荚膜组织胞浆菌感染并伴有噬血细胞综合征的病例。免疫重建炎症综合征可能是噬血细胞增多的一个危险因素。

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