von Both Ulrich, Laffer Reto, Grube Christina, Bossart Walter, Gaspert Ariana, Günthard Huldrych F
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Clin Infect Dis. 2008 Feb 15;46(4):e38-40. doi: 10.1086/526783.
Severe ulcerous cytomegalovirus pancolitis developed during primary human immunodeficiency virus (HIV) infection in a patient who underwent early combination antiretroviral treatment. This massive inflammatory process led to acute colon perforation. Serological testing demonstrated cytomegalovirus reactivation. Severe immunosuppression caused by primary HIV infection resulted in cytomegalovirus colitis, and initiation of early combination antiretroviral therapy triggered an immune reconstitution inflammatory syndrome potentially leading to colonic perforation.
一名接受早期联合抗逆转录病毒治疗的患者在原发性人类免疫缺陷病毒（HIV）感染期间发生了严重的溃疡性巨细胞病毒性全结肠炎。这种大规模的炎症过程导致了急性结肠穿孔。血清学检测显示巨细胞病毒再激活。原发性HIV感染引起的严重免疫抑制导致了巨细胞病毒性结肠炎，而早期联合抗逆转录病毒治疗的启动引发了免疫重建炎症综合征，可能导致结肠穿孔。
