Duluc I, Boukamel R, Mantei N, Semenza G, Raul F, Freund J N
INSERM U61, Strasbourg, France.
Gene. 1991 Jul 22;103(2):275-6. doi: 10.1016/0378-1119(91)90286-k.
The nucleotide sequence of the cDNA corresponding to the precursor of fetal rat intestinal lactase-phlorizin hydrolase was determined. The precursor consists of four tandemly organized homologous domains flanked by a signal peptide in the N-terminal region and by a transmembrane peptide in the C-terminal region.
测定了与胎鼠肠道乳糖酶 - 根皮苷水解酶前体相对应的cDNA的核苷酸序列。该前体由四个串联排列的同源结构域组成,其N端区域有一个信号肽,C端区域有一个跨膜肽。