Chase Daniel M, Sparks Dorothy A, Gener Melissa, Smith James
Department of Surgery, Western Reserve Care System/Northeast Ohio Universities College of Medicine, Youngstown, OH 44505, USA.
Arch Gynecol Obstet. 2009 Aug;280(2):283-6. doi: 10.1007/s00404-008-0883-1. Epub 2008 Dec 19.
Psammocarcinoma is a rare form of serous ovarian and peritoneal carcinoma, characterized by abundant psammoma bodies, invasiveness, and low-grade cytological features. Many of the cases which have been reported had extraovarian spread and peritoneal seeding at the time of presentation. We present a case of 45-year-old woman with ovarian psammocarcinoma who initially presented with a metastatic subcutaneous nodule, and was found to have pulmonary and mediastinal metastases. We believe this to be the first report of a psammocarcinoma with these metastases. Ovarian and peritoneal psammocarcinomas are quite rare, and because of this, knowledge of their behavior is limited. Although most seem to follow an indolent course similar to that of borderline lesions of the ovary, this case demonstrates that some of these tumors may be clinically aggressive with distant metastases.
砂粒体癌是浆液性卵巢癌和腹膜癌的一种罕见形式，其特征为有大量砂粒体、具有侵袭性以及低度细胞学特征。许多已报道的病例在就诊时已有卵巢外播散和腹膜种植。我们报告一例45岁患有卵巢砂粒体癌的女性，最初表现为转移性皮下结节，随后发现有肺和纵隔转移。我们认为这是首例有这些转移情况的砂粒体癌报告。卵巢和腹膜砂粒体癌非常罕见，因此，对其行为的了解有限。尽管大多数似乎遵循与卵巢交界性病变相似的惰性病程，但该病例表明其中一些肿瘤在临床上可能具有侵袭性并发生远处转移。
