Richter Melany M, Zierhut Kathrin C, Dresler Thomas, Plichta Michael M, Ehlis Ann-Christine, Reiss Kristina, Pekrun Reinhard, Fallgatter Andreas J
Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany.
J Neural Transm (Vienna). 2009 Mar;116(3):267-73. doi: 10.1007/s00702-008-0168-7. Epub 2008 Dec 19.
Solving arithmetical problems is a core skill which is learned starting early in childhood and has been shown to involve a temporo-parietal network. In this study, we investigated hemodynamic concentration changes in oxygenated (O(2)Hb) and deoxygenated hemoglobin (HHb) within cortical brain regions by means of near-infrared spectroscopy (NIRS). Ten healthy subjects had to calculate or just read two-digit addition tasks that were either presented as numeric formulas or embedded in text. We found higher increases for O(2)Hb in parietal brain regions of both hemispheres for the calculation compared to the reading-only condition. Furthermore, these increases were more pronounced during text-embedded tasks than during numeric tasks. Corresponding decreases of HHb could also be detected. These first NIRS findings on that topic confirm that parietal regions are involved in the processing of arithmetic tasks while the amount of activation seems to depend on task modalities like difficulty or complexity.
解决算术问题是一项核心技能，从儿童早期就开始学习，并且已被证明涉及一个颞顶叶网络。在本研究中，我们通过近红外光谱（NIRS）研究了大脑皮质区域内氧合血红蛋白（O(2)Hb）和脱氧血红蛋白（HHb）的血流动力学浓度变化。十名健康受试者必须计算或仅仅阅读以数字公式形式呈现或嵌入文本中的两位数加法任务。我们发现，与仅阅读条件相比，计算时两个半球顶叶脑区的O(2)Hb增加幅度更大。此外，这些增加在文本嵌入任务期间比在数字任务期间更为明显。还可以检测到HHb的相应减少。关于该主题的这些首个NIRS研究结果证实，顶叶区域参与算术任务的处理，而激活量似乎取决于任务模式，如难度或复杂性。
