Penney D P, Frank M, Fagan C, Willis C
Biological Stain Commission, Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642-0001, USA.
Biotech Histochem. 2009 Feb;84(1):11-5. doi: 10.1080/10520290802630415.
The Biological Stain Commission (BSC) Assay Laboratory has received numerous inquiries during the past several years regarding the long-term stability of stain and dye powders, particularly since packaging requirements call for expiration dates on reagents. We have conducted a study to examine the long-term stability of selected dye powders. We used the standard procedures of the BSC for testing biological stains for certification to give an indication of the long-term chemical stability as well as staining performance of the dye powders. An earlier study by Emmel and Stotz examined the stability of various dye powders after a five-year storage period. The present study is a follow-up project covering the same dyes after storage for 30 years. The dye samples chosen for the study are the same samples used in the five-year storage period study and give comparative results for all three time periods. The results of this study affirm the generally held speculation that dye powders are stable for many years and thus have a substantial shelf-life.
生物染色委员会（BSC）分析实验室在过去几年中收到了许多关于染色剂和染料粉末长期稳定性的咨询，特别是因为包装要求试剂标明有效期。我们进行了一项研究，以检验选定染料粉末的长期稳定性。我们采用了BSC检测生物染色剂以进行认证的标准程序，来表明染料粉末的长期化学稳定性以及染色性能。埃梅尔和斯托茨早期的一项研究考察了各种染料粉末在储存五年后的稳定性。本研究是一个后续项目，涵盖了储存30年后的相同染料。本研究选用的染料样品与五年储存期研究中使用的样品相同，给出了所有三个时间段的对比结果。这项研究的结果证实了普遍存在的推测，即染料粉末多年来都是稳定的，因此具有很长的保质期。
