Chi Fa-Chen, Kulkarni Suvarn S, Zulueta Medel Manuel L, Hung Shang-Cheng
Department of Chemistry, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 300, Taiwan.
Chem Asian J. 2009 Mar 2;4(3):386-90. doi: 10.1002/asia.200800406.
Making ends meet: The L-gulopyranosyl trichloroacetimidate and 1,6-anhydro-2,3-di-O-benzyl-beta-L-gulopyranose, efficiently derived from L-ascorbic acid, were individually used as a starting unit and an elongation unit to prepare L-guluronic acid linked alginate oligosaccharides in excellent alpha selectivity and in good yields.
