Chuang Heng-Chang, Chuang Cheng-Keng, Ng Kwai-Fong
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Taipei, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chang Gung Med J. 2008 Sep-Oct;31(5):515-9.
Simultaneous occurrence of multifocal urothelial carcinoma (UC) and ipsilateral renal cell carcinoma (RCC) is rare. We report a 67-year-old woman with multifocal, infiltrating urothelial carcinoma and unilateral renal cell carcinoma. She was referred to our department because of painless gross hematuria. Cystoscopy, computed tomography and retrograde pyelography studies revealed bladder, bilateral renal and ureter UC. She was treated with transurethral resection of the bladder tumor followed by bilateral nephroureterectomy. The pathological diagnosis was high-grade UC over the bladder and both renal pelves and ureters. A second tumor in the upper pole of the right kidney was reported as clear cell RCC. The patient was alive and still under careful surveillance at this writing.
多灶性尿路上皮癌（UC）与同侧肾细胞癌（RCC）同时发生的情况较为罕见。我们报告了一名67岁女性，患有多灶性浸润性尿路上皮癌和单侧肾细胞癌。她因无痛性肉眼血尿被转诊至我院。膀胱镜检查、计算机断层扫描和逆行肾盂造影研究显示膀胱、双侧肾脏和输尿管存在UC。她接受了经尿道膀胱肿瘤切除术，随后进行了双侧肾输尿管切除术。病理诊断为膀胱、双侧肾盂和输尿管的高级别UC。右肾上极的第二个肿瘤被报告为透明细胞RCC。撰写本文时，患者存活且仍在密切监测中。
