Cousins L, Baxi L, Chez R, Coustan D, Gabbe S, Harris J, Landon M, Sacks D, Singh S
Sharp Perinatal Center, San Diego, CA 92123.
Am J Obstet Gynecol. 1991 Sep;165(3):493-6. doi: 10.1016/0002-9378(91)90273-t.
As a result of extensive experiences in multiple centers and a review of the current literature, we conclude that a plasma glucose level obtained 1 hour after a 50 gm oral glucose challenge is the "best" gestational diabetes mellitus screening test. This universal screening is performed at least once during pregnancy. The screening threshold should be no higher than 140 mg/dl, or an unacceptable loss in sensitivity occurs. Universal screening for gestational diabetes mellitus is justified by morbidity reduction, cost, and protocol simplicity and ease.
基于多个中心的广泛经验以及对当前文献的回顾，我们得出结论：50克口服葡萄糖耐量试验后1小时测得的血浆葡萄糖水平是“最佳”的妊娠期糖尿病筛查试验。这种普遍筛查在孕期至少进行一次。筛查阈值不应高于140毫克/分升，否则会出现不可接受的敏感性损失。妊娠期糖尿病的普遍筛查在降低发病率、成本以及方案的简单易行方面是合理的。
