Coustan D R, Widness J A, Carpenter M W, Rotondo L, Pratt D C
Division of Maternal-Fetal Medicine, Brown University Program in Medicine, Women and Infants Hospital of Rhode Island, Providence.
Am J Obstet Gynecol. 1987 Nov;157(5):1113-7. doi: 10.1016/s0002-9378(87)80272-7.
In a group of 50 presumed normal pregnant women and 20 known gestational diabetic women, all in the early third trimester, the function of a standard 50 gm, 1-hour screening test for gestational diabetes was compared with that of a plasma glucose level determined 1 hour after the ingestion of a standard 600 kcal mixed nutrient breakfast (breakfast tolerance test). The mean plus 2 SD for the breakfast tolerance test was 120 mg/dl. If this were used as the threshold for a screening test, 75% of cases of gestational diabetes would be identified (sensitivity), while 94% of normal pregnant women would be excluded (specificity). A threshold of 100 mg/dl yields a sensitivity of 96% and a specificity of 74%. These results are compared with those for the standard 50 gm glucose challenge.
在一组50名假定正常的孕妇和20名已知患有妊娠期糖尿病的孕妇中，所有孕妇均处于孕晚期，将标准的50克1小时妊娠期糖尿病筛查试验的功能与摄入标准600千卡混合营养早餐1小时后测定的血糖水平（早餐耐量试验）的功能进行了比较。早餐耐量试验的均值加2个标准差为120毫克/分升。如果将此作为筛查试验的阈值，则可识别出75%的妊娠期糖尿病病例（敏感性），而94%的正常孕妇将被排除（特异性）。阈值为100毫克/分升时，敏感性为96%，特异性为74%。将这些结果与标准的50克葡萄糖耐量试验的结果进行了比较。
