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转移性混合性生殖细胞肿瘤之前的睾丸微石症——首例儿科报告及儿科人群睾丸微石症的推荐管理

Testicular microlithiasis preceding metastatic mixed germ cell tumor--first pediatric report and recommended management of testicular microlithiasis in the pediatric population.

作者信息

Slaughenhoupt Bruce, Kadlec Adam, Schrepferman Christopher

机构信息

University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792-3236, USA.

出版信息

Urology. 2009 May;73(5):1029-31. doi: 10.1016/j.urology.2008.09.051. Epub 2008 Dec 18.

DOI:10.1016/j.urology.2008.09.051
PMID:19100602
Abstract

Testicular microlithiasis is a condition that has been associated with testis cancer in men and boys. We report the case of a 16-year-old boy who developed metastatic mixed germ cell testicular tumor in the setting of testicular microlithiasis detected by previous ultrasonography. The tumor developed in between semiannual visits and was detected by self-examination. Chest imaging revealed 2 lung lesions, and the beta-human chorionic gonadotropin level was elevated at presentation. Because of the particular nature of healthcare surveillance in the pediatric population, we recommend annual surveillance of boys with testicular microlithiasis, including physical examination, repeated instruction regarding self-examination, and ultrasonography.

摘要

睾丸微石症是一种与男性和男孩睾丸癌相关的病症。我们报告了一例16岁男孩的病例,该男孩在之前超声检查发现有睾丸微石症的情况下,发生了转移性混合性生殖细胞睾丸肿瘤。肿瘤在半年一次的检查间期出现,并通过自我检查被发现。胸部影像学检查发现肺部有2个病灶,就诊时β-人绒毛膜促性腺激素水平升高。鉴于儿科人群医疗监测的特殊性,我们建议对患有睾丸微石症的男孩进行年度监测,包括体格检查、关于自我检查的反复指导以及超声检查。

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Testicular microlithiasis preceding metastatic mixed germ cell tumor--first pediatric report and recommended management of testicular microlithiasis in the pediatric population.转移性混合性生殖细胞肿瘤之前的睾丸微石症——首例儿科报告及儿科人群睾丸微石症的推荐管理
Urology. 2009 May;73(5):1029-31. doi: 10.1016/j.urology.2008.09.051. Epub 2008 Dec 18.
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Testicular microlithiasis: the importance of self-examination.睾丸微石症:自我检查的重要性。
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How worrisome is testicular microlithiasis?睾丸微结石症有多令人担忧?
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引用本文的文献

1
Bilateral methachronous testicular germ cell tumor and testicular microlithiasis in a child: Genetic analysis and insights. A case report.儿童双侧异时性睾丸生殖细胞肿瘤和睾丸微结石症:基因分析与见解。病例报告
Int J Surg Case Rep. 2017;41:76-79. doi: 10.1016/j.ijscr.2017.09.035. Epub 2017 Oct 15.
2
Testis tumor associated to microlithiasis.与微结石症相关的睾丸肿瘤。
Rev Paul Pediatr. 2013 Dec;31(4):554-8. doi: 10.1590/S0103-05822013000400021.
3
Ultrasound demonstration of testicular microlithiasis in pediatric patients: is there an association with testicular germ cell tumors?
超声显示小儿患者的睾丸微石症:与睾丸生殖细胞肿瘤是否有关?
Pediatr Radiol. 2014 Jan;44(1):50-5. doi: 10.1007/s00247-013-2778-y. Epub 2013 Sep 13.
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Testicular microlithiasis and epidermoid cysts: a common pathway?睾丸微结石症与表皮样囊肿:存在共同途径?
Pediatr Surg Int. 2012 Oct;28(10):1041-3. doi: 10.1007/s00383-012-3115-5. Epub 2012 Jul 5.