Vizcaíno-Alarcón A, Arévalo-Salas A, Rodríguez-López A M, Sadowinski-Pine S
Departamento de Investigaciones Cardiológicas, Hospital Infantil de México Federico Gómez, D.F.
Bol Med Hosp Infant Mex. 1991 Jun;48(6):398-408.
The records of 16 cases seen at Mexico Children's Hospital with a diagnosis of KD were reviewed. Mean age was three years; eight were infants, and males were dominant with a ratio of 4.3:1. Two cases occurred in sibling. Evidence of myocarditis was recognized in six, and 12 had coronary anomalies, including five with aneurysms. Two infants with severe coronary disease died, one suddenly with myocardial ischemia, and one with a ruptured aortic aneurysm. Another infant developed severe stenosis of the right coronary artery but remains asymptomatic. Two cases have persistent coronary ectasia and seven are asymptomatic with a normal echocardiogram. Predictors of coronary risk were correlated with clinical outcome. All six cases with 6 or more points had coronary anomalies, two developed giant aneurysms, two died and one has severe coronary stenosis. Of 10 cases with less than 6 points, four did not have coronary involvement, none developed giant aneurysms and none died nor developed severe coronary sequelae. Although KD has been sporadically reported in this country, the present series, the largest from a single institution, firmly establishes the presence of the disease in Mexico.
回顾了墨西哥儿童医院确诊为川崎病的16例病例记录。平均年龄为3岁；8例为婴儿，男性占主导，男女比例为4.3:1。2例发生在兄弟姐妹中。6例有心肌炎证据，12例有冠状动脉异常，其中5例有动脉瘤。2例患有严重冠状动脉疾病的婴儿死亡，1例因心肌缺血突然死亡，1例因主动脉瘤破裂死亡。另一名婴儿出现右冠状动脉严重狭窄，但仍无症状。2例有持续性冠状动脉扩张，7例无症状且超声心动图正常。冠状动脉风险预测因素与临床结果相关。所有6分或以上的6例均有冠状动脉异常，2例发展为巨大动脉瘤，2例死亡，1例有严重冠状动脉狭窄。10分以下的10例中，4例无冠状动脉受累，无1例发展为巨大动脉瘤，无1例死亡或出现严重冠状动脉后遗症。尽管该国曾零星报道过川崎病，但本系列病例是来自单一机构的最大规模病例，有力地证实了墨西哥存在这种疾病。
