King Roni, Lapid Roi, Epstein Ana, Bdolah-Abram Tali, Shilo Yael
Israel Nature and Parks Authority, Science an Conservation Division 3, Am Ve'Olamo Street, Jerusalem 95463, Israel.
J Zoo Wildl Med. 2008 Dec;39(4):576-81. doi: 10.1638/2008-0010.1.
Twenty-two free-ranging golden jackals (Canis aureus) were immobilized with a combination of 113 +/- 24 microg/kg medetomidine and 2.1 +/- 0.3 mg/kg ketamine (M-K) or 88 +/- 16 microg/kg medetomidine and 0.47 +/- 0.08 mg/ kg midazolam (M-M) by i.m. injection. Induction and recovery times were recorded. Pulse rate, respiratory rate, body temperature, systolic and diastolic blood pressures, and oxygen saturation were measured. Anesthesia depth indicators were observed. There was no significant difference between the M-K and the M-M groups regarding induction time (6:14 +/- 1:45 and 7:16 +/- 2:09 min, respectively). Both combinations provided safe and effective immobilization for at least 20-30 min. Pulse rate was significantly higher in the M-K group. There was no significant difference in any other objective or subjective parameter. Following administration of atipamezole at five times the dose of medetomidine given, there was a significant difference between the two combinations in recovery time; M-K jackals were standing within 3:42 +/- 2:17 min and M-M jackals within 8:47 +/- 4:32 min. Neither of the combinations caused rough or prolonged recovery. Subjectively, the M-M group had smoother and less ataxic recovery.
通过肌肉注射,将113±24微克/千克美托咪定与2.1±0.3毫克/千克氯胺酮(M-K)或88±16微克/千克美托咪定与0.47±0.08毫克/千克咪达唑仑(M-M)联合使用,对22只自由放养的金豺(金豺属)进行麻醉。记录诱导时间和恢复时间。测量脉搏率、呼吸率、体温、收缩压和舒张压以及血氧饱和度。观察麻醉深度指标。M-K组和M-M组在诱导时间方面无显著差异(分别为6:14±1:45分钟和7:16±2:09分钟)。两种组合均提供了至少20 - 30分钟的安全有效的麻醉。M-K组的脉搏率显著更高。在任何其他客观或主观参数方面均无显著差异。给予五倍于美托咪定剂量的阿替美唑后,两组在恢复时间上存在显著差异;M-K组的金豺在3:42±2:17分钟内站立,M-M组的金豺在8:47±4:32分钟内站立。两种组合均未导致粗暴或延长的恢复过程。主观上,M-M组的恢复更平稳且共济失调更少。