Supadilokluck Siraprapa, Tongprasert Fuanglada, Tongsong Theera, Wanapirak Chanane, Piyamongkol Wirawit, Sirichotiyakul Supattra, Srisupundit Kasemsri
Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Arch Gynecol Obstet. 2009 Aug;280(2):207-9. doi: 10.1007/s00404-008-0894-y. Epub 2008 Dec 27.
To describe the experiences in diagnostic amniocentesis in twin pregnancies.
The computerized database and medical records of pregnant women attending Maternal Fetal Medicine Unit of the hospital for diagnostic amniocentesis at 16-20 weeks gestation between January 1992 and December 2006 were retrospectively reviewed.
During 15 years of experience, 7,890 amniocenteses at 16-20 weeks gestation were performed for prenatal diagnosis, including 174 procedures in 87 twin pregnancies. The mean gestational age at the time of amniocentesis was 17.13 +/- 3.35 weeks. Preterm birth rate defined as the delivery before 36 gestational weeks was 36.24%. The total fetal loss rate was 5.17%, however, the procedure related fetal loss within 2 weeks after the procedure was 1.15%.
Based on our limited data and previous studies, we can counsel patients undergoing twin amniocentesis at mid-trimester that the fetal loss rate may be slightly higher than that of singleton amniocentesis.
描述双胎妊娠诊断性羊膜腔穿刺术的经验。
回顾性分析1992年1月至2006年12月期间在本院母胎医学科接受妊娠16 - 20周诊断性羊膜腔穿刺术的孕妇的计算机化数据库和病历。
在15年的经验中，共进行了7890例妊娠16 - 20周的羊膜腔穿刺术用于产前诊断，其中87例双胎妊娠进行了174次操作。羊膜腔穿刺时的平均孕周为17.13±3.35周。定义为妊娠36周前分娩的早产率为36.24%。总胎儿丢失率为5.17%，然而，操作后2周内与操作相关的胎儿丢失率为1.15%。
基于我们有限的数据和先前的研究，我们可以告知在孕中期接受双胎羊膜腔穿刺术的患者，胎儿丢失率可能略高于单胎羊膜腔穿刺术。
