Sidor Katarzyna, Semeniuk Janusz, Kaczmarski Maciej, Daniluk Urszula
Uniwersytet Medyczny w Białymstoku, III Klinika Chorób Dzieci.
Pol Merkur Lekarski. 2008 Sep;25(147):217-20.
The development of the new techniques and methods enabled to investigate the role of duodenal reflux in the pathogenesis of gastroesophageal reflux disease (GERD) therefore there is a need to establish the most common symptoms occurring in patients with duodenal reflux.
To determinate the type of manifestation and the prevalence of duodeno-gastroesophageal reflux in children and adolescents confirmed in Bilitec 2000 method.
59 patients (37 girls, 22 boys) aged 7-17 years (mean 14.7) with the symptoms of GER there were divided into 2 groups: subgroups: A--18 children with confirmed duodeno-gastroesophageal reflux in Bilitec 2000TM method and B--control consisted of 15 children with short stature referred to endoscopy due to celiac disease exclusion. In accordance to the endoscopic finding there were selected 3 subgroups: 20 patients with duodenal reflux, 19 patients with esophagitis and 20 children presenting those both disorders simultaneously. In all patients from group B the endoscopy, Bilitec 2000 and esophagitis pH metric findings haven't showed any abnormality.
The most common complain--in 16 (88.89%) patients was recurrent and/or chronic abdominal pain, next- heartburn in 12 (66.67%), vomits and/or regurgitations in 10 (55.56%) children.
The clinical manifestation of duodenal reflux was very much alike as in acid gastroeophageal reflux in the examined group. Therefore the functional gastrointestinal tract examinations have to be included in the diagnostic procedure.
新技术和方法的发展使得研究十二指肠反流在胃食管反流病（GERD）发病机制中的作用成为可能，因此有必要确定十二指肠反流患者中最常见的症状。
确定通过Bilitec 2000方法确诊的儿童和青少年十二指肠-胃食管反流的表现类型和患病率。
59例年龄在7至17岁（平均14.7岁）有GER症状的患者（37名女孩，22名男孩）被分为2组：亚组：A组——18名通过Bilitec 2000TM方法确诊为十二指肠-胃食管反流的儿童；B组——对照组，由15名因排除乳糜泻而转诊进行内镜检查的身材矮小儿童组成。根据内镜检查结果，选取3个亚组：20例十二指肠反流患者、19例食管炎患者和20例同时患有这两种疾病的儿童。B组所有患者的内镜检查、Bilitec 2000检查和食管炎pH值测量结果均未显示任何异常。
最常见的主诉——16例（88.89%）患者为反复和/或慢性腹痛，其次——12例（66.67%）为烧心，10例（55.56%）儿童有呕吐和/或反流。
在研究组中，十二指肠反流的临床表现与酸性胃食管反流非常相似。因此，功能性胃肠道检查必须纳入诊断程序。
