Nelson C C, Reed S
University of Michigan Medical Center, W. K. Kellogg Eye Center, Ann Arbor 48105.
Ophthalmic Plast Reconstr Surg. 1991;7(3):173-6. doi: 10.1097/00002341-199109000-00004.
A subset of the dry-eye patient group manifests their problem so severely that permanent punctal occlusion is required. The technique most often used today is thermal cautery. In this prospective study, an animal model was developed, and the effectiveness of the argon laser as a primary alternative therapy to thermal cautery was evaluated. Dogs were found to have a punctum similar in shape and location to humans; therefore, they were deemed to be a more appropriate animal model for punctal studies than cats. Both laser and thermal cautery are similarly effective in completely occluding puncta in animals. There was a trend toward greater stenosis with the laser in those puncta that were only partially occluded. In addition, laser punctal occlusion appeared to be less painful than thermal cautery.
一部分干眼症患者的病情非常严重，需要进行永久性泪点封闭。目前最常用的技术是热烧灼法。在这项前瞻性研究中，建立了一种动物模型，并评估了氩激光作为热烧灼法主要替代疗法的有效性。研究发现，狗的泪点在形状和位置上与人类相似；因此，它们被认为是比猫更适合用于泪点研究的动物模型。激光和热烧灼法在完全封闭动物泪点方面同样有效。对于那些仅部分封闭的泪点，激光治疗导致的狭窄程度有增大的趋势。此外，激光泪点封闭似乎比热烧灼法的疼痛感更轻。
