Knapp M E, Frueh B R, Nelson C C, Musch D C
Department of Ophthalmology, University of Michigan, W. K. Kellogg Eye Center, Ann Arbor 48105.
Am J Ophthalmol. 1989 Sep 15;108(3):315-8. doi: 10.1016/0002-9394(89)90123-2.
We performed punctal occlusion by thermal cautery on 23 patients (45 sides, 90 puncta). One punctum on the right side was randomly assigned to deep cauterization of the punctum and vertical canaliculus, and the other punctum assigned to cauterization of the punctum only. The two treatments were assigned to the opposite puncta on the left side. One month after cauterization, the puncta that received deep cauterization were significantly more likely to have remained closed than those that received superficial cauterization (P less than .01). Survival analysis over a period of follow-up that exceeded one year after surgery, using time to examination because of a reopened punctum as the endpoint, indicated a long-term advantageous effect of deep over superficial cauterization.
我们对23例患者（45侧，90个泪点）进行了热烧灼泪点封闭术。右侧的一个泪点随机分配接受泪点和垂直泪小管的深度烧灼，另一个泪点仅接受泪点烧灼。两种治疗方法分配至左侧相对的泪点。烧灼后1个月，接受深度烧灼的泪点比接受浅表烧灼的泪点更有可能保持封闭（P<0.01）。以泪点重新开放导致检查的时间为终点，对术后随访超过1年的患者进行生存分析，结果表明深度烧灼比浅表烧灼具有长期优势。
