Vad Winkler Laura, Andersen Marianne, Hørder Kirsten, Schumann Thorsten, Støving René Klinkby
Center for Eating Disorders, Odense University Hospital, Odense, Denmark.
Int J Eat Disord. 2009 Jul;42(5):475-8. doi: 10.1002/eat.20635.
Craniopharyngiomas are slow-growing tumors, which can either be asymptomatic or present themselves with visual, neuropsychiatric or endocrine disturbances. Eating disorders (EDs) are syndromes with unknown etiology, associated with multiple endocrine abnormalities. In pediatric cases the presentation of EDs may differ markedly from those of adults.
We report on two pediatric patients with craniopharyngioma misinterpreted as ED.
Available patient records, psychiatric examinations, neuro-radiographic imaging, and biochemical data were evaluated.
The reported cases illustrate the importance to consider slow-growing craniopharyngioma in ED. Especially in atypical ED, neuro-radiographic, ophthalmologic and endocrine examination should be carried out. Furthermore, structural hypothalamic lesions in these cases mimicking features of ED, suggesting the possibility of an as yet unidentified structural hypothalamic disorder to be implicated in the etiopathogeny of ED.
颅咽管瘤是生长缓慢的肿瘤，可无症状，或表现为视觉、神经精神或内分泌紊乱。饮食失调（EDs）是病因不明的综合征，与多种内分泌异常有关。在儿科病例中，EDs的表现可能与成人明显不同。
我们报告两例被误诊为ED的儿科颅咽管瘤患者。
评估现有的患者记录、精神检查、神经影像学检查和生化数据。
报告的病例说明了在ED中考虑生长缓慢的颅咽管瘤的重要性。特别是在非典型ED中，应进行神经影像学、眼科和内分泌检查。此外，这些病例中下丘脑结构病变模仿了ED的特征，提示可能存在一种尚未明确的下丘脑结构紊乱与ED的发病机制有关。
