Olsson Catharina
Department of Zoology-Zoophysiology, University of Gothenburg, Box 463, Medicinaregatan 18, SE-405 30 Göteborg, Sweden.
Acta Histochem. 2009;111(3):185-95. doi: 10.1016/j.acthis.2008.11.014. Epub 2009 Jan 4.
The enteric nervous system follows a similar overall arrangement in all vertebrate groups. In fish, the majority of nerve cell bodies are found in the myenteric plexus, innervating muscles, blood vessels and glands. In this review, I describe similarities and differences in size, shape and transmitter content in enteric neurons in different fish species and also in comparison with other vertebrates, foremost mammals. The use of different histological and immunochemical methods is reviewed in a historical perspective including advantages and disadvantages of different methods. Lately, zebrafish have become an important model species for developmental studies of the nervous system, including the enteric nervous system, and this is briefly discussed. Finally, examples of how the enteric nervous system controls gut activity in fish is presented, focussing on the effect on gastrointestinal motility.
在所有脊椎动物类群中，肠神经系统的总体布局相似。在鱼类中，大多数神经细胞体存在于肌间神经丛中，支配肌肉、血管和腺体。在这篇综述中，我描述了不同鱼类物种的肠神经元在大小、形状和递质含量方面的异同，并且与其他脊椎动物（主要是哺乳动物）进行了比较。从历史角度回顾了不同组织学和免疫化学方法的应用，包括不同方法的优缺点。最近，斑马鱼已成为神经系统发育研究（包括肠神经系统）的重要模式物种，对此也进行了简要讨论。最后，列举了肠神经系统如何控制鱼类肠道活动的例子，重点是对胃肠蠕动的影响。
