Ornstein Peter A, Schaaf Jennifer M, Hooper Stephen R, Hatton Deborah D, Mirrett Penny, Bailey Donald B
Department of Psychology, University of North Carolina at Chapel Hill, 27599-3270, USA.
Am J Ment Retard. 2008 Nov;113(6):453-65. doi: 10.1352/2008.113:453-465.
Multiple aspects of memory were examined in 42 boys with fragile X syndrome and a comparison group of 42 typically developing boys matched on MA. Working memory, incidental memory, and deliberate memory were assessed with a battery that included both free-recall and recognition tasks. Findings indicated that boys with fragile X syndrome performed more poorly than their matches on most measures. The exception was free recall, in which their accuracy was equal to that of the control participants. Results from analyses of a subset of boys with fragile X syndrome who exhibit characteristics of autism and their MA matches, though preliminary, support the conclusion that memory deficits are especially marked in boys who have fragile X syndrome and evidence autistic behaviors.
对42名患有脆性X综合征的男孩以及42名在心理年龄上与之匹配的发育正常的对照男孩的记忆多个方面进行了研究。使用一组包括自由回忆和识别任务的测试来评估工作记忆、附带记忆和有意记忆。研究结果表明，患有脆性X综合征的男孩在大多数测量指标上的表现比他们的匹配对象差。唯一的例外是自由回忆，在这方面他们的准确率与对照参与者相当。对一组表现出自闭症特征的脆性X综合征男孩及其心理年龄匹配对象的分析结果虽然是初步的，但支持了这样的结论：记忆缺陷在患有脆性X综合征且有自闭症行为迹象的男孩中尤为明显。
