脆性 X 综合征青少年和年轻男性的日常生活技能。
Daily Living Skills in Adolescent and Young Adult Males With Fragile X Syndrome.
机构信息
Angela John Thurman and Stephanie Summers Swinehart, University of California Davis Health.
Jessica Klusek and Jane E. Roberts, University of South Carolina.
出版信息
Am J Intellect Dev Disabil. 2022 Jan 1;127(1):64-83. doi: 10.1352/1944-7558-127.1.64.
Abstract
By adulthood, most males with fragile X syndrome (FXS) require support to navigate day-to-day settings. The present study cross-sectionally: (1) characterized the profile of daily living skills in males with FXS and (2) examined associated participant characteristics (i.e., fragile X mental retardation protein [FMRP] expression, nonverbal cognition, language, autism symptomatology, and anxiety symptomatology) using the Waisman-Activities of Daily Living questionnaire. Males with FXS (n = 57, ages 15-23 years) needed more help/support in the areas of domestic and community daily livings skills, than in the area of personal daily living skills. Significant associations were observed between reduced daily living skills and lower nonverbal cognition, receptive language, expressive language, and increased autism symptomatology. Receptive language emerged as the strongest unique predictor of daily living skill performance.
摘要
在成年期，大多数脆性 X 综合征（FXS）男性需要支持才能在日常生活环境中进行导航。本研究采用横断面研究方法：（1）描述 FXS 男性的日常生活技能特征；（2）使用 Waisman-日常生活活动问卷，考察相关参与者特征（即脆性 X 智力低下蛋白 [FMRP] 表达、非言语认知、语言、自闭症症状和焦虑症状）。57 名 FXS 男性（年龄 15-23 岁）在家庭和社区日常生活技能方面需要更多的帮助/支持，而在个人日常生活技能方面则相对较少。日常生活技能的下降与较低的非言语认知、接受性语言、表达性语言和增加的自闭症症状之间存在显著关联。接受性语言是日常生活技能表现的最强的唯一预测因素。
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