Hong Jaekyoung A, Bisognano John D
Department of Internal Medicine, Division of Cardiology,University of Rochester Medical Center, Rochester, NY 14642, USA.
Cardiol J. 2009;16(1):82-3.
Metoprolol succinate is a widely used medication for the management of hypertension, heart failure, and angina. We report the case of a 36-year-old woman who developed erythema multiforme after administration of a low dose of this drug. She also presented with pruritic burning pain throughout her body accompanied by chills. While erythema multiforme has been reported with carvedilol, this is the first observation of metoprolol succinate causing this and physicians should be aware of this potential, yet rare, side-effect.
琥珀酸美托洛尔是一种广泛用于治疗高血压、心力衰竭和心绞痛的药物。我们报告了一名36岁女性在服用低剂量该药物后发生多形红斑的病例。她还全身出现瘙痒性灼痛并伴有寒战。虽然已有服用卡维地洛后发生多形红斑的报道,但这是首次观察到琥珀酸美托洛尔引起这种情况,医生应意识到这种潜在但罕见的副作用。