Accorinte M L R, Loguercio A D, Reis A, Bauer J R O, Grande R H M, Murata S S, Souza V, Holland R
Department of Dental Materials, School of Dentistry, University Brás Cubas, São Paulo, SP, Brazil.
Int Endod J. 2009 Feb;42(2):122-8. doi: 10.1111/j.1365-2591.2008.01485.x.
The present randomized, controlled prospective study evaluated the histomorphological response of human dental pulps capped with two grey mineral trioxide aggregate (MTA) compounds.
Pulp exposures were performed on the occlusal floor of 40 human permanent pre-molars. The pulp was capped either with ProRoot (Dentsply) or MTA-Angelus (Angelus) and restored with zinc oxide eugenol cement. After 30 and 60 days, teeth were extracted and processed for histological examination and the effects on the pulp were scored. The data were subjected to Kruskal-Wallis and Conover tests (alpha = 0.05).
In five out of the 40 teeth bacteria were present in pulp tissue. No significant difference was observed between the two materials (P > 0.05) in terms of overall histological features (hard tissue bridge, inflammatory response, giant cells and particles of capping materials). Overall, 94% and 88% of the specimens capped with MTA-Angelus and ProRoot, respectively, showed either total or partial hard tissue bridge formation (P > 0.05).
Both commercial materials ProRoot (Dentsply) and MTA-Angelus (Angelus) produced similar responses in the pulp when used for pulp capping in intact, caries-free teeth.
本随机对照前瞻性研究评估了用两种灰色矿物三氧化物凝聚体（MTA）材料覆盖的人牙髓的组织形态学反应。
在40颗人恒牙前磨牙的咬合面上进行牙髓暴露。牙髓用ProRoot（登士柏）或MTA - Angelus（安杰卢斯）覆盖，并用氧化锌丁香酚水门汀修复。30天和60天后，拔除牙齿并进行组织学检查，对牙髓的影响进行评分。数据进行Kruskal - Wallis和Conover检验（α = 0.05）。
40颗牙齿中有5颗牙髓组织中存在细菌。两种材料在总体组织学特征（硬组织桥、炎症反应、巨细胞和覆盖材料颗粒）方面未观察到显著差异（P > 0.05）。总体而言，分别用MTA - Angelus和ProRoot覆盖的标本中，94%和88%显示出完全或部分硬组织桥形成（P > 0.05）。
当用于完整无龋牙齿的牙髓覆盖时，两种市售材料ProRoot（登士柏）和MTA - Angelus（安杰卢斯）在牙髓中产生的反应相似。
