Patra Abhinandan, Gupta Sonal, Das Asmita, Shrivastava Rohan
Department of Pedodontics and Preventive Dentistry, Kanti Devi Dental College and Hospital, Mathura, Uttar Pradesh, India.
Int J Clin Pediatr Dent. 2024 May;17(5):605-611. doi: 10.5005/jp-journals-10005-2844.
Direct pulp capping (DPC) includes covering the exposed pulp with a medication, dressing, or dental material to preserve its vitality. The idea behind this method of therapy is to induce the pulp to start a dentin bridge, "walling" the exposed site in the process. The most effective dental material to heal exposed pulp is calcium hydroxide. Mineral trioxide aggregate (MTA) causes the formation by causing cytologic and functional alterations in pulpal cells. Rosuvastatin shows pleiotropic effects like increased odontoblastic differentiation, increased mineralization, proliferation of odontoblasts, and induction of angiogenesis. Thus, the aim of the present study is to investigate pulp-dentin complex reactions following DPC with rosuvastatin vs MTA as pulp-capping materials in permanent human molars.
Patra A, Gupta S, Das A, Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study. Int J Clin Pediatr Dent 2024;17(5):605-611.
直接盖髓术(DPC)包括用药物、敷料或牙科材料覆盖暴露的牙髓以保持其活力。这种治疗方法背后的理念是诱导牙髓形成牙本质桥,在此过程中将暴露部位“封闭”起来。用于愈合暴露牙髓的最有效牙科材料是氢氧化钙。三氧化矿物凝聚体(MTA)通过引起牙髓细胞的细胞学和功能改变来促使形成(牙本质桥)。瑞舒伐他汀具有多效性作用,如增加成牙本质细胞分化、增加矿化、成牙本质细胞增殖以及诱导血管生成。因此,本研究的目的是在恒牙人类磨牙中,研究用瑞舒伐他汀与MTA作为盖髓材料进行直接盖髓术后牙髓 - 牙本质复合体的反应。
帕特拉A、古普塔S、达斯A,《瑞舒伐他汀与三氧化矿物凝聚体用于年轻成熟恒牙直接盖髓术后修复性牙本质形成的影像学评估:90天随访的裂口研究》。《国际临床儿科牙科学杂志》2024年;17(5):605 - 611。