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小梁切除术联合丝裂霉素C后中间型链球菌相关迟发性眼内炎

Streptococcus intermedius-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C.

作者信息

Mochizuki Kiyofumi, Kumada Masako, Suemori Shinsuke, Kawakami Hideaki, Sawada Akira, Yamamoto Tetsuya, Mikamo Hiroshige

机构信息

Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan.

出版信息

J Glaucoma. 2009 Jan;18(1):79-80. doi: 10.1097/IJG.0b013e318170a732.

DOI:10.1097/IJG.0b013e318170a732
PMID:19142140
Abstract

PURPOSE

To report a woman with congenital rubella syndrome of delayed-onset, bleb-related endophthalmitis induced by Streptococcus intermedius.

METHODS

Interventional case report.

RESULTS

A 33-year-old woman who underwent bilateral trabeculectomy with adjunctive mitomycin C, 11 years earlier presented with redness and blurred vision in her right eye. She had received a topical antimicrobial agent because of bleb leak before presentation. She underwent anterior chamber tap and complete vitrectomy with intravitreal antibiotics. Cultures from the vitreous aspirate grew gram-positive cocci. The DNA from the microorganism was sequenced and identified as S. intermedius. Three months after the surgical intervention, her right eye showed no residual inflammation with a best-corrected visual acuity of 30/200.

CONCLUSIONS

Bleb-associated endophthalmitis caused by S. intermedius is responsive to intravitreal antibiotics and vitrectomy, and special care should be taken to identify a bacterial pathogen.

摘要

目的

报告1例患有先天性风疹综合征、迟发性、由中间型链球菌引起的与滤过泡相关的眼内炎的女性患者。

方法

介入性病例报告。

结果

一名33岁女性,11年前接受了双侧小梁切除术并辅助使用丝裂霉素C,现出现右眼发红和视力模糊。在就诊前,她因滤过泡渗漏接受了局部抗菌药物治疗。她接受了前房穿刺和玻璃体全切除术,并眼内注射了抗生素。玻璃体抽吸物培养出革兰氏阳性球菌。对该微生物的DNA进行测序,鉴定为中间型链球菌。手术干预3个月后,她的右眼无残留炎症,最佳矫正视力为30/200。

结论

中间型链球菌引起的与滤过泡相关的眼内炎对眼内注射抗生素和玻璃体切除术有反应,应特别注意识别细菌病原体。

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