小梁切除术联合丝裂霉素C后吉氏菌属相关迟发性眼内炎

Gemella species-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C.

作者信息

Sawada Akira, Mochizuki Kiyofumi, Katada Toshihiko, Kawakami Hideaki, Yamamoto Tetsuya, Mikamo Hiroshige, Watanabe Kunitomo

机构信息

Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu-shi 501-1194, Japan.

出版信息

J Glaucoma. 2009 Aug;18(6):496-7. doi: 10.1097/IJG.0b013e31818c6f07.

DOI:10.1097/IJG.0b013e31818c6f07

PMID:19680060

Abstract

PURPOSE

To report 2 cases of delayed-onset, bleb-related endophthalmitis induced by Gemella species.

METHODS

Interventional case report.

RESULTS

Two patients developed bleb-related ocular infection attributable to Gemella haemolysans and Gemella morbillorum after trabeculectomy with adjunctive mitomycin C. Both patients had thin-walled cystic filtering blebs before ocular infection. One patient underwent urgent vitrectomy with intravitreal injection of ceftazidime and vancomycin. The other received an intraocular injection of vancomycin and ceftazidime. After surgical intervention, 2 cases were administered topical levofloxacin and sulfobenzylpenicillin, and intravenous cefpirome. The DNA from the microorganism was sequenced and identified as G. haemolysans and G. morbillorum.

CONCLUSIONS

Gemella species should be added to the long list of organisms that may rarely cause bleb-associated endophthalmitis.

摘要

目的

报告2例由孪生球菌属引起的迟发性、与滤过泡相关的眼内炎病例。

方法

介入性病例报告。

结果

2例患者在小梁切除术联合丝裂霉素C治疗后发生了由溶血孪生球菌和麻疹孪生球菌引起的与滤过泡相关的眼部感染。2例患者在眼部感染前均有薄壁囊性滤过泡。1例患者接受了紧急玻璃体切除术并玻璃体内注射头孢他啶和万古霉素。另1例接受了玻璃体内注射万古霉素和头孢他啶。手术干预后，2例患者均给予局部左氧氟沙星和磺苄西林，以及静脉注射头孢匹罗。对微生物的DNA进行测序并鉴定为溶血孪生球菌和麻疹孪生球菌。