2 型糖尿病老年患者认知表现的短期纵向趋势。
Short-term longitudinal trends in cognitive performance in older adults with type 2 diabetes.
机构信息
Department of Psychology, University of Alberta, Edmonton, Alberta, Canada.
出版信息
J Clin Exp Neuropsychol. 2009 Oct;31(7):809-22. doi: 10.1080/13803390802537636. Epub 2009 Feb 17.
Abstract
Type 2 diabetes is associated with cognitive deficits, although inconsistently across neuropsychological domains. We examined 3-year longitudinal data from the Victoria Longitudinal Study, comparing diabetes (n = 28) and control (n = 272) older adults on a comprehensive neuropsychological battery. Assessing potential change and stability, we found that (a) baseline diabetes group deficits in semantic speed and speed-intensive executive function were preserved, (b) new average deficits for reaction time and nonspeeded executive function appeared, and (c) no differential short-term change was observed. It is clinically and theoretically important to examine sequential change in multiple domains over time.
摘要
2 型糖尿病与认知缺陷有关，尽管在神经心理学领域的表现并不一致。我们研究了来自维多利亚纵向研究的 3 年纵向数据，比较了糖尿病（n = 28）和对照组（n = 272）老年人在综合神经心理学测试中的表现。评估潜在的变化和稳定性，我们发现：(a) 基线时糖尿病组在语义速度和速度密集型执行功能方面的缺陷得到了保留；(b) 出现了新的平均反应时间和非速度执行功能缺陷；(c) 没有观察到短期差异变化。从临床上和理论上讲，重要的是要随着时间的推移检查多个领域的连续变化。
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