探究2型糖尿病对老年人认知功能的影响。
Exploring effects of type 2 diabetes on cognitive functioning in older adults.
作者信息
Yeung Sophie E, Fischer Ashley L, Dixon Roger A
机构信息
Department of Psychology, University of Alberta.
出版信息
Neuropsychology. 2009 Jan;23(1):1-9. doi: 10.1037/a0013849.
Type 2 diabetes may be associated with exacerbated aging-related declines in cognitive neuropsychological performance. The authors examined whether such effects are systematic (i.e., broadly distributed across domains or domain-specific) or moderated by age (i.e., varying across age within older adults). The authors assembled recent cross-sectional data from the Victoria Longitudinal Study (VLS) Sample 3 (Wave 1; initial n = 570; initial age = 53-90 years). Using a comprehensive, multidimensional spectrum of cognitive neuropsychological tests, the authors examined performance differences by diabetes status (diabetes group vs. healthy controls) and age (young-old vs. old-old). Our results showed that healthy controls significantly outperformed the diabetes group only on markers of executive functioning and speed. Notably, the diabetes-related effects were robust across the two late-life age groups. Future research examining longitudinal changes is recommended.
2型糖尿病可能与衰老相关的认知神经心理表现衰退加剧有关。作者研究了这些影响是系统性的（即广泛分布于各个领域还是特定领域的）还是受年龄调节的（即老年人中随年龄变化）。作者收集了来自维多利亚纵向研究（VLS）样本3（第1波；初始n = 570；初始年龄 = 53 - 90岁）的近期横断面数据。通过使用全面的、多维度的认知神经心理测试，作者研究了糖尿病状态（糖尿病组与健康对照组）和年龄（年轻老年人与年老老年人）对表现的差异。我们的结果表明，健康对照组仅在执行功能和速度指标上显著优于糖尿病组。值得注意的是，与糖尿病相关的影响在两个老年年龄组中都很显著。建议未来进行研究以考察纵向变化。
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