Zhang J
Zhongshan Ophthalmic Centre, Sun Yat-sen University of Medical Sciences, Guangzhou.
Zhonghua Yan Ke Za Zhi. 1991 May;27(3):151-3.
92 trabeculectomy specimens of congenital glaucoma, aged 35 days to 46 years, were studied by light and transmission electron microscopy, with findings of narrowed anterior chamber angle, thickened ciliary muscle displaced forward, and crooked or thickened trabeculae, many disintegrated with hyaloid degeneration. The cribriform meshwork appeared dense, with deposition of fibrillae and collagen or basement membrane-like material; Schlemm's canal was absent in 3 specimens; in some the lumen was narrowed or locally obliterated; and Descemet membrane-like substance covered the trabecular meshwork. The types of pathological changes, their relationship with the symptoms, and the locations of outflow resistance were discussed.
对92例年龄在35天至46岁之间的先天性青光眼小梁切除术标本进行了光镜和透射电镜研究，结果发现前房角变窄、睫状肌增厚并向前移位、小梁弯曲或增厚，许多小梁出现透明样变性并解体。筛状板显得致密，有纤维和胶原或基底膜样物质沉积；3个标本中没有施莱姆管；在一些标本中，管腔变窄或局部闭塞；并且有类似Descemet膜的物质覆盖小梁网。讨论了病理变化的类型、它们与症状的关系以及房水流出阻力的部位。
