Ultrastructural observations of the anterior chamber angle tissues in congenital glaucoma.

Eighteen trabeculectomy specimens of congenital glaucoma were examined by light and transmission electron microscopy. The results showed that the primary anomalies in congenital glaucoma included the developmental defects of trabecular meshwork, excessive collagen fibrils in the trabecular matrix, shifting forward of ciliary muscle fibres and persistent mesenchymal tissues in the anterior-chamber angle. The authors also pointed out the importance of the secondary lesions of the trabecular meshwork in the pathogenesis of congenital glaucoma.