Harling H, Hegnhøj J, Rasmussen T N, Jarnum S
Department of Surgical Gastroenterology C, Rigshospitalet, University of Copenhagen, Denmark.
Dis Colon Rectum. 1991 Oct;34(10):931-5. doi: 10.1007/BF02049711.
Eighty-four patients had colectomy with ileostomy and oversewing of the rectum for Crohn's colitis. Seventy-two patients were operated on because of intractable disease, colitis in combination with rectal fistulas, and toxic megacolon. The operative mortality was 6 percent, and neither emergency surgery nor treatment with steroids correlated with operative morbidity. After a median 7.7 years of follow-up, 25 ileorectal anastomoses had been undertaken, 16 of which were successful. Twenty-nine protectomies were performed; the resulting 10-year cumulative risk of proctectomy was 50 percent. While the risk of proctectomy was significantly less among patients with a normal rectum at colectomy compared with patients with proctitis, the initial macroscopic degree of proctitis did not correlate with the risk of subsequent proctectomy. The 5-year cumulative ileal resection rate in 29 patients with a rectum in situ but out of circuit was 29 percent. The possibility of a future ileorectal anastomosis should still be considered in patients with proctocolitis.
84例患有克罗恩病性结肠炎的患者接受了结肠切除术并回肠造口,同时直肠缝闭。72例患者因病情顽固、结肠炎合并直肠瘘以及中毒性巨结肠而接受手术。手术死亡率为6%,急诊手术和类固醇治疗均与手术并发症无关。经过中位7.7年的随访,进行了25例回直肠吻合术,其中16例成功。进行了29例直肠切除术;直肠切除术后10年的累积风险为50%。与患有直肠炎的患者相比,结肠切除时直肠正常的患者直肠切除风险显著更低,但直肠炎的初始宏观程度与随后直肠切除的风险无关。29例直肠原位但已旷置的患者5年回肠切除累积率为29%。对于患有直肠结肠炎的患者,仍应考虑未来进行回直肠吻合术的可能性。