Melegh Zsombor, Sutak Judit, Whiteway Alastair, Rooney Nicholas, Pawade Joya
Department of Histopathology, Level 9, Bristol Royal Infirmary, Marlborough Street, Bristol BS28HW, UK.
Pathol Res Pract. 2009;205(5):371-4. doi: 10.1016/j.prp.2008.11.004. Epub 2009 Jan 14.
Lymphomatoid granulomatosis is an Epstein-Barr virus-driven lymphoproliferative disorder, usually with a prominent pulmonary involvement and occasional extrapulmonary manifestations. Here, we present a case of lymphomatoid granulomatosis confined to the uterine cervix at the initial diagnosis. The disease was preceded by an immunosuppressive condition, namely low-grade lymphoplasmacytic lymphoma treated with chemotherapy. This is the first report of lymphomatoid granulomatosis at this site and emphasizes that it can present at unusual sites, such as the female genital tract in immunosuppressed patients.
淋巴瘤样肉芽肿病是一种由爱泼斯坦-巴尔病毒驱动的淋巴增殖性疾病,通常有显著的肺部受累,偶尔有肺外表现。在此,我们报告一例初诊时局限于子宫颈的淋巴瘤样肉芽肿病病例。该疾病之前存在免疫抑制状态,即接受化疗的低度淋巴浆细胞淋巴瘤。这是该部位淋巴瘤样肉芽肿病的首例报告,并强调其可出现在不寻常的部位,如免疫抑制患者的女性生殖道。