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心血管疾病风险筛查与精神困扰无关:Inter99研究。

Screening for risk of cardiovascular disease is not associated with mental distress: the Inter99 study.

作者信息

Jørgensen Torben, Ladelund Steen, Borch-Johnsen Knut, Pisinger Charlotta, Schrader Anne-Marie, Thomsen Troels, Glümer Charlotte, Ibsen Hans, Mortensen Erik Lykke

机构信息

Research Centre for Prevention and Health, Building 84/85, Glostrup University Hospital, DK-2600 Glostrup, Denmark.

出版信息

Prev Med. 2009 Mar;48(3):242-6. doi: 10.1016/j.ypmed.2008.12.010. Epub 2008 Dec 25.

Abstract

OBJECTIVE

To analyze mental distress in relation to participation in lifestyle intervention.

METHODS

In 2000-2001 a total of 1948 consecutive participants, living in the suburbs of Copenhagen, were asked to complete a short version of SCL-90-R (anxiety, depression, and somatization) before screening, immediately after screening, and one and 10 months after screening. The screening classified participants into high or low risk individuals. High risk individuals received personal lifestyle counselling and were randomized to either group-based counselling (A) or referred care (B). Multilevel regression models taking into account repeated measurements and missing data at follow-up were performed.

RESULTS

Before screening, high risk individuals had higher scores on anxiety, depression, and somatization than low risk individuals. All categories of participants decreased in scores after screening. The scores increased after 1 month, but were still significantly lower than before screening. After 10 months, low risk individuals and high risk individuals in group A still had significantly lower scores (except for depression) compared with pre-screening levels, whereas high risk individuals in group B reached the pre-screening level (except for anxiety).

CONCLUSION

Screening for risk of cardiovascular disease followed by health counselling does not give rise to mental distress, but has a temporary beneficial effect.

摘要

目的

分析与参与生活方式干预相关的心理困扰。

方法

在2000 - 2001年,共有1948名连续的参与者,居住在哥本哈根郊区,被要求在筛查前、筛查后立即、筛查后1个月和10个月完成SCL - 90 - R简版(焦虑、抑郁和躯体化)。筛查将参与者分为高风险或低风险个体。高风险个体接受个人生活方式咨询,并被随机分为基于小组的咨询(A组)或转诊护理(B组)。进行了考虑重复测量和随访时缺失数据的多水平回归模型分析。

结果

筛查前,高风险个体在焦虑、抑郁和躯体化方面的得分高于低风险个体。所有类别的参与者在筛查后的得分均下降。得分在1个月后有所上升,但仍显著低于筛查前。10个月后,与筛查前水平相比,A组的低风险个体和高风险个体的得分(除抑郁外)仍显著较低,而B组的高风险个体达到了筛查前水平(除焦虑外)。

结论

筛查心血管疾病风险并随后进行健康咨询不会引发心理困扰,反而有暂时的有益效果。

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