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母源呼吸道合胞病毒抗体的季节性变化及其与婴儿呼吸道合胞病毒住院治疗的关联。

Seasonal variation of maternally derived respiratory syncytial virus antibodies and association with infant hospitalizations for respiratory syncytial virus.

作者信息

Stensballe Lone Graff, Ravn Henrik, Kristensen Kim, Meakins Tiffany, Aaby Peter, Simoes Eric A F

机构信息

Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark.

出版信息

J Pediatr. 2009 Feb;154(2):296-8. doi: 10.1016/j.jpeds.2008.07.053.

DOI:10.1016/j.jpeds.2008.07.053
PMID:19150677
Abstract

This study used 459 prospectively sampled cord blood samples to examine the association between maternally derived respiratory syncytial virus (RSV)-neutralizing antibodies and the RSV hospitalization season in Denmark. We found a clear temporal association and suggest that RSV-neutralizing antibody level plays a role in the RSV seasonal pattern.

摘要

本研究使用了459份前瞻性采集的脐带血样本，以检测丹麦母体来源的呼吸道合胞病毒（RSV）中和抗体与RSV住院季节之间的关联。我们发现了明确的时间关联，并表明RSV中和抗体水平在RSV季节性模式中发挥作用。

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