Dorfman Todd A, Iskandrian Ami E
Division of Cardiovascular Diseases, Department of Medicine, The University of Alabama at Birmingham, LHRB 306, 1530 3rd Avenue S, Birmingham, AL 35294-0007, USA.
J Nucl Cardiol. 2009 Jan-Feb;16(1):122-34. doi: 10.1007/s12350-008-9015-3. Epub 2009 Jan 20.
Takotsubo cardiomyopathy (TC) is characterized by transient, often severe, left ventricular dysfunction and electrocardiographic changes that might mimic acute myocardial infarction in the absence of significant obstructive coronary artery disease. It is often encountered in elderly women after physical or emotional stress. Excessive catecholamine stimulation, metabolic abnormalities, and microcirculatory dysfunction are thought to be responsible for the manifestations of this disorder. This comprehensive review summarizes relevant published data, atypical presentations, pathophysiology, and management strategy. It also includes a review of 789 patients with TC including nine illustrative cases encountered at our institution.
应激性心肌病（TC）的特征是短暂性、常为严重的左心室功能障碍以及心电图改变，这些改变在无显著阻塞性冠状动脉疾病的情况下可能类似急性心肌梗死。它常在老年女性经历身体或情绪应激后出现。儿茶酚胺过度刺激、代谢异常和微循环功能障碍被认为是该疾病表现的原因。这篇综述总结了相关已发表的数据、非典型表现、病理生理学和管理策略。它还包括对789例应激性心肌病患者的回顾，其中包括我们机构遇到的9例典型病例。
