Havens Jennifer R, Stoops William W, Leukefeld Carl G, Garrity Thomas F, Carlson Robert G, Falck Russel, Wang Jichuan, Booth Brenda M
Center on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Am J Drug Alcohol Abuse. 2009;35(1):18-23. doi: 10.1080/00952990802326298.
The purpose of the current analysis was to examine the factors associated with prescription opiate misuse among stimulant users from rural counties in Arkansas, Kentucky, and Ohio (N = 714).
Multiple logistic regression was utilized to determine the independent correlates of recent (prior 6 months) prescription opiate misuse.
More than half of participants (53.2%) reported prescription opiate misuse in the previous 6 months. Other drug use (heroin, cocaine, methamphetamine, and marijuana) and anxiety (Adjusted Odds Ratio: 2.04, 95% Confidence Interval: 1.60, 2.59) were independently associated with prescription opiate misuse. Chronic pain and other health indicators were not associated with prescription opiate misuse after adjustment for covariates.
Results indicate that illicit drug involvement and psychiatric symptoms may be driving the high rates of prescription opiate misuse among rural stimulant users. These findings have implications for the provision of treatment in resource-deprived rural areas.
本次分析的目的是研究阿肯色州、肯塔基州和俄亥俄州农村县的兴奋剂使用者中与处方阿片类药物滥用相关的因素(N = 714)。
采用多元逻辑回归来确定近期(前6个月)处方阿片类药物滥用的独立相关因素。
超过一半的参与者(53.2%)报告在过去6个月中存在处方阿片类药物滥用情况。其他药物使用(海洛因、可卡因、甲基苯丙胺和大麻)以及焦虑(调整后的优势比:2.04,95%置信区间:1.60,2.59)与处方阿片类药物滥用独立相关。在对协变量进行调整后,慢性疼痛和其他健康指标与处方阿片类药物滥用无关。
结果表明,非法药物使用和精神症状可能是农村兴奋剂使用者处方阿片类药物滥用率高的原因。这些发现对资源匮乏的农村地区的治疗提供具有启示意义。