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农村和城市非医疗处方类阿片使用者的终身和近期药物使用情况比较。

A comparison of rural and urban nonmedical prescription opioid users' lifetime and recent drug use.

机构信息

College of Public Health, University of Kentucky, Lexington, USA.

出版信息

Am J Drug Alcohol Abuse. 2012 May;38(3):220-7. doi: 10.3109/00952990.2011.643971. Epub 2012 Jan 3.

Abstract

BACKGROUND

Nonmedical prescription opioid use has emerged as a major public health concern. The growing burden of nonmedical prescription opioid use in America may have unique manifestations and consequences in rural areas, which to a large extent have yet to be explored.

OBJECTIVES

To describe rural-urban differences among drug users in recent and lifetime use and age of onset of use for alcohol, heroin, OxyContin(®), oxycodone, hydrocodone, barbiturates, benzodiazepines, cocaine, crack, methamphetamine, amphetamine, marijuana, hallucinogens, and inhalants.

METHODS

A purposive sample of 212 prescription drug users was recruited from a rural Appalachian county (n = 101) and a major metropolitan area (n = 111) in Kentucky. Consenting participants were given an interviewer-administered questionnaire examining sociodemographics, psychiatric characteristics, and self-reported drug use.

RESULTS

Rural drug users had significantly earlier ages of onset for use of oxycodone, hydrocodone, benzodiazepines, cocaine, and crack. In age-, gender-, and race-adjusted logistic regression analyses, rural drug users had significantly higher odds of lifetime and recent use of methadone, OxyContin(®), and oxycodone. Rural drug users also had significantly higher odds of lifetime cocaine and crack use. However, urban participants as expected had significantly higher odds of recent crack use.

CONCLUSIONS

The findings demonstrate that, in this sample, nonmedical prescription opioid use is dissimilar among rural and urban drug users. Additional research is needed to better understand the individual, social, and structural level factors contributing to the burden of nonmedical opioid use, particularly in rural populations, with the aim of developing tailored substance abuse treatment and prevention.

摘要

背景

非医疗处方类阿片类药物的使用已成为一个主要的公共卫生问题。在美国,非医疗处方类阿片类药物的使用负担不断增加,这在很大程度上尚未在农村地区得到充分探索。

目的

描述近期和终生使用药物以及使用药物的起始年龄在城乡药物使用者之间的差异,这些差异在很大程度上尚未得到充分探索。

方法

在肯塔基州的一个农村阿巴拉契亚县(n = 101)和一个主要大都市区(n = 111),我们采用目的抽样法招募了 212 名处方药物使用者。同意参与的参与者接受了访谈者管理的问卷调查,调查内容包括社会人口统计学特征、精神科特征和自我报告的药物使用情况。

结果

农村药物使用者使用羟考酮、氢可酮、苯二氮䓬类药物、可卡因和快克的起始年龄明显更早。在年龄、性别和种族调整后的逻辑回归分析中,农村药物使用者终生和近期使用美沙酮、羟考酮和奥施康定(OxyContin(®))的可能性显著更高。农村药物使用者终生使用可卡因和快克的可能性也显著更高。然而,如预期的那样,城市参与者近期使用快克的可能性显著更高。

结论

这些发现表明,在本研究样本中,城乡药物使用者的非医疗处方类阿片类药物使用情况存在差异。需要进一步研究,以更好地了解导致非医疗类阿片类药物使用负担的个体、社会和结构层面的因素,特别是在农村人群中,旨在制定针对特定人群的药物滥用治疗和预防措施。

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